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nup88 nucleoporin 88 [ Danio rerio (zebrafish) ]

Gene ID: 321744, updated on 9-Dec-2024

Summary

Official Symbol
nup88provided by ZNC
Official Full Name
nucleoporin 88provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-297
See related
Ensembl:ENSDARG00000003235 AllianceGenome:ZFIN:ZDB-GENE-050522-297
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb16f10; wu:fb33e09; zgc:112439; ik:tdsubc_2f7; xx:tdsubc_2f7
Summary
Predicted to be a structural constituent of nuclear pore. Predicted to be involved in nucleocytoplasmic transport. Predicted to act upstream of or within mRNA transport; nucleocytoplasmic transport; and protein transport. Predicted to be located in nucleus. Predicted to be part of nuclear pore. Is expressed in several structures, including brain; eye; immature eye; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in fetal akinesia deformation sequence syndrome 4. Orthologous to human NUP88 (nucleoporin 88). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See nup88 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (59089699..59111962, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (58419990..58442253, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene SLP adaptor and CSK interacting membrane protein Neighboring gene rabaptin, RAB GTPase binding effector protein 1 Neighboring gene VPS37D subunit of ESCRT-I Neighboring gene PRKR interacting protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural constituent of nuclear pore IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within mRNA transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nucleocytoplasmic transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal large subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within ribosomal large subunit export from nucleus IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within ribosomal small subunit export from nucleus IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of nuclear pore IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
nucleoporin 88
Names
nuclear pore complex protein Nup88

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020466.1NP_001018302.1  nucleoporin 88

    See identical proteins and their annotated locations for NP_001018302.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095815
    UniProtKB/Swiss-Prot
    A0A2R8QUY6, A2CEI4, Q501Y6
    Related
    ENSDARP00000025718.7, ENSDART00000023123.8
    Conserved Domains (1) summary
    pfam10168
    Location:8719
    Nup88; Nuclear pore component

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    59089699..59111962 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394619.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    75305..95231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)