ckmt1 creatine kinase, mitochondrial 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ckmt1provided by ZNC
Official Full Name: creatine kinase, mitochondrial 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-611
See related: Ensembl:ENSDARG00000016598 AllianceGenome:ZFIN:ZDB-GENE-030131-611
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb37h03; fb69a12; wu:fb37h03; wu:fb69a12
Summary: Predicted to enable creatine kinase activity. Predicted to be involved in phosphocreatine biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in nervous system; pleuroperitoneal region; and yolk syncytial layer. Orthologous to human CKMT1A (creatine kinase, mitochondrial 1A) and CKMT1B (creatine kinase, mitochondrial 1B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 25

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (21830019..21847553)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (21732471..21750005)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb37h03.x1 (e-PCR)
- UniSTS:203161

AI544906 (e-PCR)
- UniSTS:206302

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables creatine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables creatine kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity, transferring phosphorus-containing groups	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in phosphocreatine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphocreatine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: creatine kinase, mitochondrial 1

NP_942096.1

EC 2.7.3.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198801.1 → NP_942096.1 creatine kinase, mitochondrial 1

See identical proteins and their annotated locations for NP_942096.1

Status: PROVISIONAL

Source sequence(s)

BC048050

UniProtKB/TrEMBL

A0A2R8PZ48, B2GSL6, Q7ZUN7

Related

ENSDARP00000011271.6, ENSDART00000027393.8

Conserved Domains (1) summary

cd00716
Location:50 → 407

creatine_kinase_like; Phosphagen (guanidino) kinases such as creatine kinase and similar enzymes