U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gtf2a1 general transcription factor IIA, 1 [ Danio rerio (zebrafish) ]

Gene ID: 323974, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
gtf2a1provided by ZNC
Official Full Name
general transcription factor IIA, 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2694
See related
Ensembl:ENSDARG00000011000 AllianceGenome:ZFIN:ZDB-GENE-030131-2694
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tf2a; fc15h02; fj36b10; zgc:55847; wu:fc15h02; wu:fj36b10
Summary
Predicted to be involved in transcription by RNA polymerase II. Predicted to act upstream of or within transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIA complex. Orthologous to human GTF2A1 (general transcription factor IIA subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See gtf2a1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (16437741..16453572, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (16538158..16553989, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 52 Neighboring gene U5 spliceosomal RNA Neighboring gene uncharacterized LOC137488629 Neighboring gene checkpoint suppressor 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS. Tingaud-Sequeira A, et al. Mol Genet Genomic Med, 2020 Oct. PMID 32738032, Free PMC Article
  2. Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos. Gehrig J, et al. Nat Methods, 2009 Dec. PMID 19898487
  3. Multiple thyrotropin β-subunit and thyrotropin receptor-related genes arose during vertebrate evolution. Maugars G, et al. PLoS One, 2014. PMID 25386660, Free PMC Article
  4. Identification of zygotic genes expressed at the midblastula transition in zebrafish. O'Boyle S, et al. Biochem Biophys Res Commun, 2007 Jun 29. PMID 17490614
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transcription initiation at RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIIA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIIA complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
transcription initiation factor IIA subunit 1
Names
general transcription factor IIA, 1, 19/37kDa

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212657.1 → NP_997822.1  transcription initiation factor IIA subunit 1

    See identical proteins and their annotated locations for NP_997822.1

    Status: PROVISIONAL

    Source sequence(s)
    BC048894
    UniProtKB/TrEMBL
    Q7ZUK2
    Related
    ENSDARP00000015974.5, ENSDART00000006443.7
    Conserved Domains (2) summary
    cd07976
    Location:312 → 369
    TFIIA_alpha_beta_like; Precursor of TFIIA alpha and beta subunits and similar proteins
    pfam03153
    Location:13 → 369
    TFIIA; Transcription factor IIA, alpha/beta subunit

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    16437741..16453572 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.