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sec22a SEC22 homolog A, vesicle trafficking protein [ Danio rerio (zebrafish) ]

Gene ID: 324832, updated on 12-Sep-2024

Summary

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Official Symbol
sec22aprovided by ZNC
Official Full Name
SEC22 homolog A, vesicle trafficking proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3553
See related
Ensembl:ENSDARG00000078328 AllianceGenome:ZFIN:ZDB-GENE-030131-3553
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc44f07; sec22l2; zgc:56686; wu:fc44f07
Summary
Predicted to act upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Orthologous to human SEC22A (SEC22 homolog A, vesicle trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See sec22a in Genome Data Viewer
Location:
chromosome: 9
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (37850425..37860493)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (38040666..38050698)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba Neighboring gene uncharacterized LOC137496490 Neighboring gene uncharacterized LOC137496491 Neighboring gene protein disulfide isomerase family A, member 5 Neighboring gene adenylate cyclase 5 Neighboring gene 3-hydroxyacyl-CoA dehydratase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters. Vacca F, et al. J Physiol, 2022 May. PMID 35413133, Free PMC Article
  2. B cells in teleost fish act as pivotal initiating APCs in priming adaptive immunity: an evolutionary perspective on the origin of the B-1 cell subset and B7 molecules. Zhu LY, et al. J Immunol, 2014 Mar 15. PMID 24532580
  3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
vesicle-trafficking protein SEC22a
Names
SEC22 vesicle trafficking protein homolog A
SEC22 vesicle trafficking protein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199698.1 → NP_955992.1  vesicle-trafficking protein SEC22a

    See identical proteins and their annotated locations for NP_955992.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049530
    UniProtKB/TrEMBL
    Q7ZW89
    Related
    ENSDARP00000076602.5, ENSDART00000082165.7
    Conserved Domains (2) summary
    COG5143
    Location:8 → 146
    SNC1; Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]
    pfam13774
    Location:38 → 106
    Longin; Regulated-SNARE-like domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    37850425..37860493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478609.2 → XP_021334284.1  vesicle-trafficking protein SEC22a isoform X1

    UniProtKB/TrEMBL
    A0A8M9QAL1, F1QBW3
    Conserved Domains (1) summary
    pfam13774
    Location:38 → 114
    Longin; Regulated-SNARE-like domain
Nucleotide Protein
Heading Accession and Version

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