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glipr2 GLI pathogenesis-related 2 [ Danio rerio (zebrafish) ]

Gene ID: 325699, updated on 9-Dec-2024

Summary

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Official Symbol
glipr2provided by ZNC
Official Full Name
GLI pathogenesis-related 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4424
See related
Ensembl:ENSDARG00000041724 AllianceGenome:ZFIN:ZDB-GENE-030131-4424
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fd05a10; im:6795575; wu:fd05a10; si:dkey-2n12.1
Summary
Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in blood cell and vascular endothelium. Orthologous to human GLIPR2 (GLI pathogenesis related 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See glipr2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (33028079..33039783, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (32427763..32439570, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene LIM domain only 4a Neighboring gene zgc:55461 Neighboring gene neuropeptide FF receptor 2 Neighboring gene uncharacterized LOC100001344 Neighboring gene KN motif and ankyrin repeat domains 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular development. Hensley MR, et al. Sci Rep, 2016 Jun 13. PMID 27292017, Free PMC Article
  2. Characterization of retinoid-X receptor genes rxra, rxrba, rxrbb and rxrg during zebrafish development. Tallafuss A, et al. Gene Expr Patterns, 2006 Jun. PMID 16448862
  3. Genome-wide analysis of the zebrafish Klf family identifies two genes important for erythroid maturation. Xue Y, et al. Dev Biol, 2015 Jul 15. PMID 26015096
  4. Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development. Cannon JE, et al. Mech Dev, 2013 Feb. PMID 23072875, Free PMC Article
  5. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
GLI pathogenesis-related 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001423664.1 → NP_001410593.1  GLI pathogenesis-related 2

    Status: VALIDATED

    Source sequence(s)
    CR855258
    UniProtKB/TrEMBL
    A0A8M9PR01, A0A8M9QEP8, A2CF32
    Related
    ENSDARP00000118616.1, ENSDART00000141361.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    33028079..33039783 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476526.2 → XP_021332201.1  GLI pathogenesis-related 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PEW6, A0A8M9PR01
    Conserved Domains (3) summary
    cd05382
    Location:126 → 256
    SCP_GAPR-1_like; SCP-like extracellular protein domain, golgi-associated plant pathogenesis related protein (GAPR)-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory ...
    cl00133
    Location:2 → 65
    SCP; SCP-like extracellular protein domain, found in eukaryotes and prokaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), which accumulates after infections with pathogens, and may act as an anti-fungal agent or be involved in cell ...
    cl27373
    Location:223 → 329
    PapD_C; Pili assembly chaperone PapD, C-terminal domain

  2. XM_068221100.1 → XP_068077201.1  GLI pathogenesis-related 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PR01

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394587.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    128131..140189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395240.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    299117..310817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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