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dnajb1b DnaJ heat shock protein family (Hsp40) member B1b [ Danio rerio (zebrafish) ]

Gene ID: 327244, updated on 2-Nov-2024

Summary

Official Symbol
dnajb1bprovided by ZNC
Official Full Name
DnaJ heat shock protein family (Hsp40) member B1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5455
See related
Ensembl:ENSDARG00000041394 AllianceGenome:ZFIN:ZDB-GENE-030131-5455
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dnj-13C; fd19c10; zgc:55492; wu:fd19c10; CH73-341P18.4
Summary
Predicted to enable Hsp70 protein binding activity; transcription corepressor activity; and unfolded protein binding activity. Acts upstream of or within lens development in camera-type eye. Predicted to be active in cytosol. Is expressed in lens; neural plate; optic tectum; and solid lens vesicle. Orthologous to human DNAJB1 (DnaJ heat shock protein family (Hsp40) member B1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See dnajb1b in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (55745709..55750266, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (55068227..55072346, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor E3 Neighboring gene adhesion G protein-coupled receptor E3-like Neighboring gene adhesion G protein-coupled receptor E10 Neighboring gene trans-2,3-enoyl-CoA reductase b Neighboring gene NADH:ubiquinone oxidoreductase subunit B7

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables Hsp70 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within lens development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein folding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
dnaJ homolog subfamily B member 1b
Names
DnaJ (Hsp40) homolog, subfamily B, member 1
DnaJ (Hsp40) homolog, subfamily B, member 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199773.2NP_956067.2  dnaJ homolog subfamily B member 1b

    Status: VALIDATED

    Source sequence(s)
    CU571167
    Related
    ENSDARP00000121420.2, ENSDART00000142244.3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    55745709..55750266 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)