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cndp2 carnosine dipeptidase 2 [ Danio rerio (zebrafish) ]

Gene ID: 327288, updated on 4-Jan-2025

Summary

Official Symbol
cndp2provided by ZNC
Official Full Name
carnosine dipeptidase 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5499
See related
Ensembl:ENSDARG00000003931 AllianceGenome:ZFIN:ZDB-GENE-030131-5499
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
CN2; zgc:92569; wu:fd20d11; wu:fe17f09
Summary
Predicted to enable dipeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytosol. Is expressed in several structures, including intermediate cell mass of mesoderm; lens; neural crest; solid lens vesicle; and yolk syncytial layer. Orthologous to human CNDP2 (carnosine dipeptidase 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See cndp2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (20801066..20823101)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (21216741..21238778)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488436 Neighboring gene ADNP homeobox 2b Neighboring gene thioredoxin-like 4A Neighboring gene uncharacterized LOC137488506 Neighboring gene teashirt zinc finger homeobox 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables dipeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables dipeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metallodipeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
cytosolic non-specific dipeptidase
Names
CNDP dipeptidase 2 (metallopeptidase M20 family)
NP_999869.2
XP_005170061.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214704.2NP_999869.2  cytosolic non-specific dipeptidase

    See identical proteins and their annotated locations for NP_999869.2

    Status: VALIDATED

    Source sequence(s)
    BQ263633, BX957344, DY546953, EH500533
    UniProtKB/TrEMBL
    A0A8M1PK12, A3KQX1
    Related
    ENSDARP00000033632.5, ENSDART00000038202.6
    Conserved Domains (1) summary
    cd05676
    Location:7473
    M20_dipept_like_CNDP; M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    20801066..20823101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170004.5XP_005170061.1  cytosolic non-specific dipeptidase isoform X1

    See identical proteins and their annotated locations for XP_005170061.1

    UniProtKB/TrEMBL
    A0A8M1PK12, A3KQX1
    Related
    ENSDARP00000120032.2, ENSDART00000143457.4
    Conserved Domains (1) summary
    cd05676
    Location:7473
    M20_dipept_like_CNDP; M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase