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CG8051 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32925, updated on 18-Sep-2024

Summary

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Official Symbol
CG8051provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031012
Locus tag
Dmel_CG8051
See related
AllianceGenome:FB:FBgn0031012
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO03002137.1; Dmel\CG8051; EP(X)1550
Summary
Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be integral component of membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in cataract 47 and familial hyperinsulinemic hypoglycemia 7. Orthologous to several human genes including SLC16A1 (solute carrier family 16 member 1); SLC16A12 (solute carrier family 16 member 12); and SLC16A3 (solute carrier family 16 member 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG8051 in Genome Data Viewer
Location:
18C1-18C1; 1-62 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19301330..19307925, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19195363..19201958, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene small non-coding RNA 763 Neighboring gene outsiders Neighboring gene nicotinic Acetylcholine Receptor alpha7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Divergent evolution and purifying selection of the Type 2 diabetes gene sequences in Drosophila: a phylogenomic study. Gupta MK, et al. Genetica, 2020 Dec. PMID 32804315
  2. Glial Glycolysis Is Essential for Neuronal Survival in Drosophila. Volkenhoff A, et al. Cell Metab, 2015 Sep 1. PMID 26235423
  3. RNomics in Drosophila melanogaster: identification of 66 candidates for novel non-messenger RNAs. Yuan G, et al. Nucleic Acids Res, 2003 May 15. PMID 12736298, Free PMC Article
  4. A misexpression study examining dorsal thorax formation in Drosophila melanogaster. Peña-Rangel MT, et al. Genetics, 2002 Mar. PMID 11901120, Free PMC Article
  5. The Drosophila surface glia transcriptome: evolutionary conserved blood-brain barrier processes. DeSalvo MK, et al. Front Neurosci, 2014. PMID 25426014, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables monocarboxylic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monocarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8051-PA
CG8051-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    19301330..19307925 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_133149.3 → NP_573377.1  uncharacterized protein Dmel_CG8051, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573377.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9A0, Q9VWJ0
    Related
    FBpp0074452
    Conserved Domains (2) summary
    cd06174
    Location:86 → 266
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:440 → 572
    MFS_1; Major Facilitator Superfamily

  2. NM_001298505.1 → NP_001285434.1  uncharacterized protein Dmel_CG8051, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285434.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9A0, Q9VWJ0
    Conserved Domains (2) summary
    cd06174
    Location:86 → 266
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:440 → 572
    MFS_1; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VWJ0 Q9VWJ0

Gene LinkOut

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