Gm14325 predicted gene 14325 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gm14325provided by MGI
Official Full Name: predicted gene 14325provided by MGI
Primary source: MGI:MGI:3702875
See related: Ensembl:ENSMUSG00000095362 AllianceGenome:MGI:3702875
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in bladder adult (RPKM 6.1), cerebellum adult (RPKM 5.3) and 21 other tissues See more
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Genomic context

Location:: 2 H4; 2 99.53 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (177470784..177482129, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (177828991..177840336, complement)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: novel KRAB box and zinc finger, C2H2 type domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024849.3 → NP_001020020.2 novel KRAB box and zinc finger, C2H2 type domain containing protein

Status: VALIDATED

Source sequence(s)

AL935320

Consensus CDS

CCDS71209.1

UniProtKB/TrEMBL

A2AW67

Related

ENSMUSP00000104567.3, ENSMUST00000108939.9

Conserved Domains (5) summary

smart00349
Location:5 → 45

KRAB; krueppel associated box

COG5048
Location:74 → 459

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:161 → 181

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:5 → 43

KRAB; KRAB box

pfam13465
Location:201 → 226

zf-H2C2_2; Zinc-finger double domain