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wtap WT1 associated protein [ Danio rerio (zebrafish) ]

Gene ID: 334058, updated on 9-Dec-2024

Summary

Official Symbol
wtapprovided by ZNC
Official Full Name
WT1 associated proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5990
See related
Ensembl:ENSDARG00000042642 AllianceGenome:ZFIN:ZDB-GENE-030131-5990
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:66202; wu:fi29a09
Summary
Acts upstream of or within regulation of apoptotic process. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of RNA N6-methyladenosine methyltransferase complex. Predicted to be active in nucleus. Is expressed in head. Orthologous to human WTAP (WT1 associated protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See wtap in Genome Data Viewer
Location:
chromosome: 20
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (30931414..30938187, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (31028535..31035367, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene kinesin family member 25 Neighboring gene acetyl-CoA acetyltransferase 2 Neighboring gene superoxide dismutase 2, mitochondrial Neighboring gene fibronectin type III domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA modification IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of alternative mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of RNA N6-methyladenosine methyltransferase complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nuclear speck ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
pre-mRNA-splicing regulator WTAP
Names
Wilms tumor 1 associated protein
Wilms' tumour 1-associating protein
female-lethal(2)D homolog
wilms tumor 1-associating protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199853.1NP_956147.1  pre-mRNA-splicing regulator WTAP

    See identical proteins and their annotated locations for NP_956147.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055544
    UniProtKB/Swiss-Prot
    Q7SXL7
    Related
    ENSDARP00000062551.4, ENSDART00000062552.6
    Conserved Domains (1) summary
    pfam17098
    Location:1246
    Wtap; Pre-mRNA-splicing regulator WTAP

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    30931414..30938187 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)