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ddx23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [ Danio rerio (zebrafish) ]

Gene ID: 334283, updated on 2-Nov-2024

Summary

Official Symbol
ddx23provided by ZNC
Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6215
See related
Ensembl:ENSDARG00000021945 AllianceGenome:ZFIN:ZDB-GENE-030131-6215
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63742; wu:fi39b12
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human DDX23 (DEAD-box helicase 23). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See ddx23 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (14193548..14216496, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (14437471..14460419, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene adenylate cyclase 6a Neighboring gene calcium channel, voltage-dependent, beta 3a Neighboring gene baculoviral IAP repeat containing 7 Neighboring gene uncharacterized LOC137489102

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
probable ATP-dependent RNA helicase DDX23
NP_956176.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199882.1NP_956176.1  probable ATP-dependent RNA helicase DDX23

    See identical proteins and their annotated locations for NP_956176.1

    Status: PROVISIONAL

    Source sequence(s)
    BC060524
    UniProtKB/TrEMBL
    A0A8M1PG28, Q6P9Z2
    Related
    ENSDARP00000007528.9, ENSDART00000019620.10
    Conserved Domains (3) summary
    smart00487
    Location:393629
    DEXDc; DEAD-like helicases superfamily
    cd00268
    Location:380616
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam00271
    Location:637746
    Helicase_C; Helicase conserved C-terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    14193548..14216496 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395135.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    173533..197079 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395358.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    422906..438479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)