atp13a1 ATPase 13A1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atp13a1provided by ZNC
Official Full Name: ATPase 13A1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2804
See related: Ensembl:ENSDARG00000029931 AllianceGenome:ZFIN:ZDB-GENE-040426-2804
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: atp13a; zgc:63781; wu:fi75c10; hm:zehn0386
Summary: Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity; P-type ion transporter activity; and membrane protein dislocase activity. Predicted to be involved in extraction of mislocalized protein from ER membrane; intracellular calcium ion homeostasis; and transmembrane transport. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ATP13A1 (ATPase 13A1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (52899801..52952026)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (52645138..52697363)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled monoatomic cation transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables P-type ion transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables P-type transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables membrane protein dislocase activity	IBA Inferred from Biological aspect of Ancestor more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in extraction of mislocalized protein from ER membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular calcium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: endoplasmic reticulum transmembrane helix translocase

Names: ATPase type 13A; ATPase type 13A1

NP_001001403.2

EC 7.2.2.10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001403.2 → NP_001001403.2 endoplasmic reticulum transmembrane helix translocase

Status: PROVISIONAL

Source sequence(s)

CT573476

UniProtKB/TrEMBL

A0A8M1MZL3, F1R1X4

Related

ENSDARP00000058957.5, ENSDART00000058958.6

Conserved Domains (3) summary

COG4087
Location:804 → 861

COG4087; Soluble P-type ATPase [General function prediction only]

TIGR01657
Location:84 → 1155

P-ATPase-V; P-type ATPase of unknown pump specificity (type V)

pfam00122
Location:277 → 485

E1-E2_ATPase; E1-E2 ATPase