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mapre1b microtubule-associated protein, RP/EB family, member 1b [ Danio rerio (zebrafish) ]

Gene ID: 334728, updated on 4-Jan-2025

Summary

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Official Symbol
mapre1bprovided by ZNC
Official Full Name
microtubule-associated protein, RP/EB family, member 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2256
See related
Ensembl:ENSDARG00000002659 AllianceGenome:ZFIN:ZDB-GENE-040426-2256
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mapre1; zgc:85755; wu:fa01e12; wu:fc23e11
Summary
Predicted to enable microtubule binding activity. Predicted to act upstream of or within cell division. Predicted to be located in plasma membrane. Is expressed in oocyte stage IV and ovarian follicle stage IV. Orthologous to human MAPRE1 (microtubule associated protein RP/EB family member 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See mapre1b in Genome Data Viewer
Location:
chromosome: 23
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (9794679..9807560, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (9859709..9872618, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene ADRM1 26S proteasome ubiquitin receptor Neighboring gene laminin, alpha 5 Neighboring gene protein kinase C binding protein 1, like Neighboring gene si:ch211-220i18.4 Neighboring gene solute carrier family 16 member 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Staufen1, Kinesin1 and microtubule function in cyclin B1 mRNA transport to the animal polar cytoplasm of zebrafish oocytes. Takahashi K, et al. Biochem Biophys Res Commun, 2018 Sep 18. PMID 30103945
  2. The Role of MAPRE2 and Microtubules in Maintaining Normal Ventricular Conduction. Chiang DY, et al. Circ Res, 2024 Jan 5. PMID 38095085
  3. Targeting the Microtubule EB1-CLASP2 Complex Modulates Na(V)1.5 at Intercalated Discs. Marchal GA, et al. Circ Res, 2021 Jul 23. PMID 34092082, Free PMC Article
  4. Transcriptomic Profiling Revealed Signaling Pathways Associated with the Spawning of Female Zebrafish under Cold Stress. Ge G, et al. Int J Mol Sci, 2022 Jul 6. PMID 35886843, Free PMC Article
  5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
microtubule-associated protein RP/EB family member 1b
Names
microtubule-associated protein, RP/EB family, member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213640.1 → NP_998805.1  microtubule-associated protein RP/EB family member 1b

    See identical proteins and their annotated locations for NP_998805.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068377
    UniProtKB/TrEMBL
    A0A8M1PJQ9, Q6NUY9
    Related
    ENSDARP00000010960.7, ENSDART00000004474.9
    Conserved Domains (2) summary
    pfam00307
    Location:16 → 100
    CH; Calponin homology (CH) domain
    pfam03271
    Location:203 → 240
    EB1; EB1-like C-terminal motif

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    9794679..9807560 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005161949.4 → XP_005162006.2  microtubule-associated protein RP/EB family member 1b isoform X1

    UniProtKB/TrEMBL
    A0A8M2B926
    Related
    ENSDARP00000120869.1, ENSDART00000136740.3
    Conserved Domains (3) summary
    COG5217
    Location:16 → 269
    BIM1; Microtubule-binding protein involved in cell cycle control [Cell division and chromosome partitioning / Cytoskeleton]
    pfam00307
    Location:16 → 100
    CH; Calponin homology (CH) domain
    pfam03271
    Location:219 → 256
    EB1; EB1-like C-terminal motif
Nucleotide Protein Strain
Heading Accession and Version

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