sh3glb1b SH3-domain GRB2-like endophilin B1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sh3glb1bprovided by ZNC
Official Full Name: SH3-domain GRB2-like endophilin B1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6851
See related: Ensembl:ENSDARG00000010956 AllianceGenome:ZFIN:ZDB-GENE-030131-6851
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: sh3glb1; im:5777505; wu:fa08f03; wu:fb13e12
Summary: Predicted to be involved in membrane organization. Predicted to act upstream of or within apoptotic process. Predicted to be located in Golgi membrane and mitochondrial outer membrane. Predicted to be active in membrane. Orthologous to human SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (16174046..16194196)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (16505452..16525606)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fa08f03.s1 (e-PCR)
- UniSTS:202261

fb13e12.x1 (e-PCR)
- UniSTS:202900

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within apoptotic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: endophilin-B1b

Names: SH3-domain GRB2-like endophilin B1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001256616.1 → NP_001243545.1 endophilin-B1b

Status: VALIDATED

Source sequence(s)

CR788310

UniProtKB/TrEMBL

A0A8M1NZI7, B0V151

Related

ENSDARP00000045932.6, ENSDART00000045933.7

Conserved Domains (2) summary

cd11945
Location:300 → 360

SH3_Endophilin_B1; Src homology 3 domain of Endophilin-B1

cl12013
Location:21 → 249

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007113.7 Reference GRCz11 Primary Assembly

Range

16174046..16194196

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005163307.5 → XP_005163364.1 endophilin-B1b isoform X1

UniProtKB/TrEMBL

A0A0R4IS36, A0A8M2BAQ1

Related

ENSDARP00000138573.2, ENSDART00000157601.2

Conserved Domains (2) summary

cd11945
Location:337 → 397

SH3_Endophilin_B1; Src homology 3 domain of Endophilin-B1

cl12013
Location:21 → 286

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_068223128.1 → XP_068079229.1 endophilin-B1b isoform X2

Related

ENSDARP00000143647.1, ENSDART00000177639.2