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fam76b family with sequence similarity 76 member B [ Danio rerio (zebrafish) ]

Gene ID: 335015, updated on 2-Nov-2024

Summary

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Official Symbol
fam76bprovided by ZNC
Official Full Name
family with sequence similarity 76 member Bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6955
See related
Ensembl:ENSDARG00000012432 AllianceGenome:ZFIN:ZDB-GENE-030131-6955
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa11h02; zgc:73333; wu:fa11h02
Summary
Predicted to be active in nuclear speck. Orthologous to human FAM76B (family with sequence similarity 76 member B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See fam76b in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (23585215..23596317, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (23081414..23092546, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase long chain family member 4b Neighboring gene CWC15 spliceosome associated protein homolog Neighboring gene K(lysine) acetyltransferase 5a Neighboring gene myotubularin related protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Expression and functional analysis of fam76b in zebrafish. Zhu J, et al. Fish Shellfish Immunol, 2023 Nov. PMID 37838209
  2. RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation. Rösel TD, et al. EMBO J, 2011 May 18. PMID 21468032, Free PMC Article
  3. New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens. Tseng LC, et al. PLoS One, 2014. PMID 24714733, Free PMC Article
  4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear speck ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
protein FAM76B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199932.1 → NP_956226.1  protein FAM76B

    See identical proteins and their annotated locations for NP_956226.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059652
    UniProtKB/Swiss-Prot
    Q6PBM7
    Related
    ENSDARP00000026447.7, ENSDART00000024815.8
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 317
    FAM76; FAM76 protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    23585215..23596317 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009301288.4 → XP_009299563.1  protein FAM76B isoform X1

    UniProtKB/TrEMBL
    A0A8M3B2A7
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 316
    FAM76; FAM76 protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PBM7.1 GenPept UniProtKB/Swiss-Prot:Q6PBM7

Gene LinkOut

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