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anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A [ Danio rerio (zebrafish) ]

Gene ID: 335907, updated on 2-Nov-2024

Summary

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Official Symbol
anp32aprovided by ZNC
Official Full Name
acidic (leucine-rich) nuclear phosphoprotein 32 family, member Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7850
See related
Ensembl:ENSDARG00000006487 AllianceGenome:ZFIN:ZDB-GENE-030131-7850
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:55516; wu:fj36e08
Summary
Predicted to enable histone binding activity. Predicted to be involved in nucleocytoplasmic transport and regulation of apoptotic process. Predicted to be located in endoplasmic reticulum and perinuclear region of cytoplasm. Predicted to be active in nucleus. Orthologous to several human genes including ANP32A (acidic nuclear phosphoprotein 32 family member A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See anp32a in Genome Data Viewer
Location:
chromosome: 7
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (33345627..33350002, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (33074477..33078852, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496180 Neighboring gene coronin, actin binding protein, 2Ba Neighboring gene glucuronic acid epimerase b Neighboring gene progestin and adipoQ receptor family member Vb

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Anp32a Promotes Neuronal Regeneration after Spinal Cord Injury of Zebrafish Embryos. Lee HC, et al. Int J Mol Sci, 2022 Dec 14. PMID 36555564, Free PMC Article
  2. The Anp32 family of proteins containing leucine-rich repeats. Matilla A, et al. Cerebellum, 2005. PMID 15895553
  3. A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure. Ayobahan SU, et al. Sci Rep, 2019 Apr 29. PMID 31036921, Free PMC Article
  4. Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target. Raman R, et al. Sci Rep, 2021 Jul 27. PMID 34315984, Free PMC Article
  5. High-Resolution Proteomic Profiling Shows Sexual Dimorphism in Zebrafish Heart-Associated Proteins. Niksirat H, et al. J Proteome Res, 2021 Aug 6. PMID 34185526

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in nucleocytoplasmic transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
acidic leucine-rich nuclear phosphoprotein 32 family member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199986.1 → NP_956280.1  acidic leucine-rich nuclear phosphoprotein 32 family member A

    See identical proteins and their annotated locations for NP_956280.1

    Status: PROVISIONAL

    Source sequence(s)
    BC048047
    UniProtKB/Swiss-Prot
    Q7ZUP0
    UniProtKB/TrEMBL
    B2GSB4
    Related
    ENSDARP00000022360.6, ENSDART00000008785.9
    Conserved Domains (3) summary
    smart00446
    Location:128 → 146
    LRRcap; occurring C-terminal to leucine-rich repeats
    sd00033
    Location:90 → 114
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:88 → 130
    LRR_4; Leucine Rich repeats (2 copies)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    33345627..33350002 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7ZUP0.1 GenPept UniProtKB/Swiss-Prot:Q7ZUP0

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