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ppm1g protein phosphatase, Mg2+/Mn2+ dependent, 1G [ Danio rerio (zebrafish) ]

Gene ID: 368275, updated on 9-Dec-2024

Summary

Official Symbol
ppm1gprovided by ZNC
Official Full Name
protein phosphatase, Mg2+/Mn2+ dependent, 1Gprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030425-4
See related
Ensembl:ENSDARG00000075559 AllianceGenome:ZFIN:ZDB-GENE-030425-4
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb167; wu:fb37b10; wu:fe01e01
Summary
Predicted to enable metal ion binding activity and myosin phosphatase activity. Acts upstream of or within central nervous system development. Predicted to be active in nucleoplasm. Is expressed in several structures, including nervous system; neural tube; pectoral fin bud; pectoral fin musculature; and pharyngeal arch. Orthologous to human PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See ppm1g in Genome Data Viewer
Location:
chromosome: 13
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (6188759..6205567)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (6060299..6077114)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene deltaD Neighboring gene family with sequence similarity 120 member B Neighboring gene si:zfos-1056e6.1 Neighboring gene adipocyte plasma membrane associated protein

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cation binding IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within central nervous system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein phosphatase 1G
NP_958896.1
XP_005169569.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201488.1NP_958896.1  protein phosphatase 1G

    See identical proteins and their annotated locations for NP_958896.1

    Status: PROVISIONAL

    Source sequence(s)
    BC052132
    UniProtKB/TrEMBL
    Q7ZTW5
    Conserved Domains (2) summary
    smart00332
    Location:24109
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
    pfam00481
    Location:324486
    PP2C; Protein phosphatase 2C

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    6188759..6205567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169512.5XP_005169569.1  protein phosphatase 1G isoform X1

    UniProtKB/TrEMBL
    A0A8M2BGW3, F1QJE5
    Related
    ENSDARP00000102878.2, ENSDART00000109665.3
    Conserved Domains (2) summary
    smart00332
    Location:24109
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
    cd00143
    Location:323502
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...