mdga2a MAM domain containing glycosylphosphatidylinositol anchor 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mdga2aprovided by ZNC
Official Full Name: MAM domain containing glycosylphosphatidylinositol anchor 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030616-360
See related: Ensembl:ENSDARG00000024017 AllianceGenome:ZFIN:ZDB-GENE-030616-360
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mamdc1; si:dz209d10.1
Summary: Acts upstream of or within facial nerve formation; regulation of motor neuron migration; and trigeminal motor nucleus development. Predicted to be located in cytoplasm and membrane. Is expressed in several structures, including brainstem; cranial nerve; muscle; pharyngeal musculature; and posterior lateral line. Orthologous to human MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (28340148..28565634)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (28323162..28548671)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Process	Evidence Code	Pubs
acts_upstream_of_or_within facial nerve formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of motor neuron migration	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within trigeminal motor nucleus development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

Preferred Names: MAM domain-containing glycosylphosphatidylinositol anchor protein 2

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_021473195.2 → XP_021328870.1 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform X1

UniProtKB/TrEMBL

A0A8M9Q6Q8

Conserved Domains (5) summary

smart00408
Location:256 → 317

IGc2; Immunoglobulin C-2 Type

smart00409
Location:154 → 222

IG; Immunoglobulin

pfam00629
Location:754 → 928

MAM; MAM domain, meprin/A5/mu

pfam13927
Location:50 → 114

Ig_3; Immunoglobulin domain

cl28434
Location:349 → 420

I-set; Immunoglobulin I-set domain
XM_021473197.2 → XP_021328872.1 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform X2

UniProtKB/TrEMBL

A0A8M6YTC4, F1RDD1

Conserved Domains (5) summary

smart00408
Location:256 → 317

IGc2; Immunoglobulin C-2 Type

smart00409
Location:154 → 222

IG; Immunoglobulin

pfam00629
Location:748 → 922

MAM; MAM domain, meprin/A5/mu

pfam13927
Location:50 → 114

Ig_3; Immunoglobulin domain

cl28434
Location:349 → 420

I-set; Immunoglobulin I-set domain
XM_068218883.1 → XP_068074984.1 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform X3
XM_068218884.1 → XP_068074985.1 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform X4