asnsd1 asparagine synthetase domain containing 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: asnsd1provided by ZNC
Official Full Name: asparagine synthetase domain containing 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030616-362
See related: Ensembl:ENSDARG00000000540 AllianceGenome:ZFIN:ZDB-GENE-030616-362
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56584; si:dz211o13.6; si:busm1-211o13.6
Summary: Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity. Predicted to act upstream of or within asparagine biosynthetic process and glutamine metabolic process. Orthologous to human ASNSD1 (asparagine synthetase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (41083103..41090067, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (41281320..41288281, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables asparagine synthase (glutamine-hydrolyzing) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within amino acid biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within asparagine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glutamine metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: asparagine synthetase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200095.2 → NP_956389.2 asparagine synthetase domain-containing protein 1

Status: VALIDATED

Source sequence(s)

CT737230

UniProtKB/Swiss-Prot

Q7ZTT7, Q8JFW1

UniProtKB/TrEMBL

A0A8M6Z0V6, B0V348, F6PB16

Related

ENSDARP00000001119.9, ENSDART00000000564.9

Conserved Domains (2) summary

cd01991
Location:280 → 588

Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...

cd03766
Location:1 → 178

Gn_AT_II_novel; Gn_AT_II_novel. This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007120.7 Reference GRCz11 Primary Assembly

Range

41083103..41090067 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017357660.2 → XP_017213149.1 asparagine synthetase domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

B0V348

Related

ENSDARP00000123026.1, ENSDART00000131681.3

Conserved Domains (2) summary

cd01991
Location:280 → 588

Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...

cd03766
Location:1 → 178

Gn_AT_II_novel; Gn_AT_II_novel. This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, ...