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Skel Skeletor [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772559, updated on 18-Sep-2024

Summary

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Official Symbol
Skelprovided by FlyBase
Official Full Name
Skeletorprovided by FlyBase
Primary source
FLYBASE:FBgn0262717
Locus tag
Dmel_CG43161
See related
AllianceGenome:FB:FBgn0262717
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
2Ab3; CG14681; CG14682; CG31261; CG32922; CG33676; CG43161; Dmel\CG43161; skeletor
Old locus tag
Dmel_CG14681; Dmel_CG33676
Summary
Enables structural molecule activity. Involved in spindle assembly. Located in nucleus and polytene chromosome. Is expressed in embryonic head sensory system. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Skel in Genome Data Viewer
Location:
86C4-86C4; 3-50 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10686943..10696270)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6512665..6521992)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Phytanoyl-CoA dioxygenase domain containing 1 Neighboring gene long non-coding RNA:CR44230 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pugilist Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Searching for a spindle matrix. Wells WA. J Cell Biol, 2001 Sep 17. PMID 11564751, Free PMC Article
  2. Remodeling of nuclear architecture during the cell cycle in Drosophila embryos. Johansen KM, et al. J Cell Biochem, 1996 Dec 1. PMID 8913878
  3. Dynamic remodeling of nuclear architecture during the cell cycle. Johansen KM. J Cell Biochem, 1996 Mar 1. PMID 8867805
  4. EAST interacts with Megator and localizes to the putative spindle matrix during mitosis in Drosophila. Qi H, et al. J Cell Biochem, 2005 Aug 15. PMID 15962301
  5. Chromator, a novel and essential chromodomain protein interacts directly with the putative spindle matrix protein skeletor. Rath U, et al. J Cell Biochem, 2004 Nov 15. PMID 15389869

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural molecule activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleus organization NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in spindle assembly IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in polytene chromosome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
skeletor
Names
CG43161-PB
CG43161-PC
CG43161-PD
CG43161-PE
Skel-PB
Skel-PC
Skel-PD
Skel-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    10686943..10696270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001032002.2 → NP_001027173.2  skeletor, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027173.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9GPJ1

  2. NM_001260098.1 → NP_001247027.1  skeletor, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247027.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8T0R5, Q9GPJ1
    UniProtKB/TrEMBL
    A0A0B4K6P5
    Conserved Domains (2) summary
    smart00686
    Location:158 → 264
    DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
    smart00664
    Location:286 → 447
    DoH; Possible catecholamine-binding domain present in a variety of eukaryotic proteins

  3. NM_001032000.2 → NP_001027171.1  skeletor, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027171.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9EQQ8, Q7YU64, Q9VGY6, Q9VGY7
    Conserved Domains (2) summary
    smart00686
    Location:158 → 264
    DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
    smart00664
    Location:286 → 447
    DoH; Possible catecholamine-binding domain present in a variety of eukaryotic proteins

  4. NM_001032001.2 → NP_001027172.1  skeletor, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027172.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VGY6
    Conserved Domains (1) summary
    smart00686
    Location:158 → 264
    DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K6P5 A0A0B4K6P5
Q9GPJ1.3 Q9GPJ1
Q9VGY6.2 Q9VGY6

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