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BRRF1 protein G49 [ Human gammaherpesvirus 4 (Epstein-Barr virus) ]

Gene ID: 3783728, updated on 20-Nov-2023

Summary

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Gene symbol
BRRF1
Gene description
protein G49
Locus tag
HHV4_BRRF1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Human gammaherpesvirus 4 (strain: B95-8, strain: Raji, type: 1, common: Epstein-Barr virus, acronym: EBV, acronym: HHV-4, nat-host: Homo sapiens)
Lineage
Viruses; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus
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Genomic context

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Sequence:
NC_007605.1 (92728..93827)

NC_007605.1Genomic Context describing neighboring genes Neighboring gene nuclear antigen EBNA-3B;nuclear antigen EBNA-3C Neighboring gene protein-coding Neighboring gene nuclear antigen EBNA-1 Neighboring gene envelope glycoprotein 42 Neighboring gene protein Zta Neighboring gene protein Rta Neighboring gene tegument protein G48 Neighboring gene envelope glycoprotein L Neighboring gene uracil-DNA glycosylase Neighboring gene tegument protein G45

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007605.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EBI2 expression in B lymphocytes is controlled by the Epstein-Barr virus transcription factor, BRRF1 (Na), during viral infection. Cornaby C, et al. J Gen Virol, 2017 Mar. PMID 27902324
  2. The Epstein-Barr virus BRRF1 protein, Na, induces lytic infection in a TRAF2- and p53-dependent manner. Hagemeier SR, et al. J Virol, 2011 May. PMID 21325409, Free PMC Article
  3. Updated Epstein-Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV. de Jesus O, et al. J Gen Virol, 2003 Jun. PMID 12771413
  4. The EB virus genome in Daudi Burkitt's lymphoma cells has a deletion similar to that observed in a non-transforming strain (P3HR-1) of the virus. Jones MD, et al. EMBO J, 1984 Apr. PMID 6327290, Free PMC Article
  5. Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcript. Jeang KT, et al. J Virol, 1983 Oct. PMID 6310141, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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regulatory

  • Loc: 92728-92733 regulatory_class = TATA_box
  • Loc: 93822-93827 regulatory_class = polyA_signal_sequence

General protein information

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Preferred Names
protein G49

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007605.1 Reference assembly

    Range
    92728..93827
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_401675.1 protein G49 [Human gammaherpesvirus 4]

    See identical proteins and their annotated locations for YP_401675.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03207, P0C722, P0C723, Q777E3
    UniProtKB/TrEMBL
    A0A0B6VHF8, A0A0C7TAR5, A0A0C7TJ09, A0A0C7TJV3, A0A0S2YRI9, A0A0X8XBR8, A0A2S1MQ39, A0A4D6TWM8, A0A4D6TWQ0, G3CKR2
    Conserved Domains (1) summary
    cl27986
    Location:22 → 302
    Herpes_BBRF1; BRRF1-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C722.1

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