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tspan2a tetraspanin 2a [ Danio rerio (zebrafish) ]

Gene ID: 378854, updated on 2-Nov-2024

Summary

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Official Symbol
tspan2aprovided by ZNC
Official Full Name
tetraspanin 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-511
See related
Ensembl:ENSDARG00000003754 AllianceGenome:ZFIN:ZDB-GENE-050522-511
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tspan2; sb:cb834; wu:fb82d08; wu:fj10e11; zgc:110586
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in olfactory placode and peripheral olfactory organ. Orthologous to human TSPAN2 (tetraspanin 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See tspan2a in Genome Data Viewer
Location:
chromosome: 6
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (49107048..49159094, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (49108395..49160441, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene thyroid stimulating hormone subunit beta a Neighboring gene solute carrier family 25 member 55a Neighboring gene uncharacterized LOC137496020 Neighboring gene nerve growth factor b (beta polypeptide) Neighboring gene si:dkey-183k8.2 Neighboring gene uncharacterized LOC137495892

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Multiple thyrotropin β-subunit and thyrotropin receptor-related genes arose during vertebrate evolution. Maugars G, et al. PLoS One, 2014. PMID 25386660, Free PMC Article
  2. Molecular evolution and functional divergence of zebrafish (Danio rerio) cryptochrome genes. Liu C, et al. Sci Rep, 2015 Jan 29. PMID 25630924, Free PMC Article
  3. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tetraspanin-2a
Names
TSPAN2-1
tetraspanin 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001018150.1 → NP_001018160.1  tetraspanin-2a

    See identical proteins and their annotated locations for NP_001018160.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095323
    UniProtKB/TrEMBL
    A0A8M1N5L7, Q503H8
    Related
    ENSDARP00000041941.7, ENSDART00000041942.8
    Conserved Domains (2) summary
    cl02781
    Location:110 → 176
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:10 → 204
    Tetraspannin; Tetraspanin family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    49107048..49159094 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394668.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    206451..243323 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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