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LINC01550 long intergenic non-protein coding RNA 1550 [ Homo sapiens (human) ]

Gene ID: 388011, updated on 22-Oct-2024

Summary

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Official Symbol
LINC01550provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1550provided by HGNC
Primary source
HGNC:HGNC:20111
See related
Ensembl:ENSG00000246223 AllianceGenome:HGNC:20111
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C14orf64
Expression
Broad expression in skin (RPKM 2.3), lymph node (RPKM 1.7) and 22 other tissues See more
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Genomic context

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See LINC01550 in Genome Data Viewer
Location:
14q32.2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (97925610..97978124, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (92158116..92210608, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (98391947..98444461, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2291 Neighboring gene uncharacterized LOC124903377 Neighboring gene uncharacterized LOC105370650 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9001 Neighboring gene uncharacterized LOC105370651 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr14:98178659-98179858 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr14:98213528-98214158 Neighboring gene long intergenic non-protein coding RNA 2312 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:98315519-98315728 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:98334809-98334984 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:98415455-98415954 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:98444461-98444960 Neighboring gene uncharacterized LOC107984706 Neighboring gene uncharacterized LOC105370655 Neighboring gene uncharacterized LOC105370654

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Long noncoding RNA LINC01550 inhibits colorectal cancer malignancy by suppressing the Wnt/β-catenin signaling pathway. Wu W, et al. J Biochem Mol Toxicol, 2024 Aug. PMID 39041324
  2. Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma. Chen J, et al. Med Oncol, 2021 Feb 20. PMID 33609219
  3. MIMT1 and LINC01550 are uncharted lncRNAs down-regulated in colorectal cancer. Vejdandoust F, et al. Int J Exp Pathol, 2023 Jun. PMID 36727289, Free PMC Article
  4. Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. Zhao SX, et al. Hum Mol Genet, 2013 Aug 15. PMID 23612905
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long noncoding RNA LINC01550 inhibits colorectal cancer malignancy by suppressing the Wnt/beta-catenin signaling pathway.
    Title: Long noncoding RNA LINC01550 inhibits colorectal cancer malignancy by suppressing the Wnt/β-catenin signaling pathway.
  2. MIMT1 and LINC01550 are uncharted lncRNAs down-regulated in colorectal cancer.
    Title: MIMT1 and LINC01550 are uncharted lncRNAs down-regulated in colorectal cancer.
  3. Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma.
    Title: Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_015430.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL352981, KF456003

  2. NR_152746.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL352981
    Related
    ENST00000502187.6

  3. NR_152747.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL352981
    Related
    ENST00000512901.6

  4. NR_152748.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL352981

  5. NR_152749.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL352981
    Related
    ENST00000652825.1

  6. NR_152750.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL352981
    Related
    ENST00000556462.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    97925610..97978124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    92158116..92210608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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