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SAOUHSC_00069 protein A [ Staphylococcus aureus subsp. aureus NCTC 8325 ]

Gene ID: 3919448, updated on 6-Oct-2023

Summary

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Gene symbol
SAOUHSC_00069
Gene description
protein A
Locus tag
SAOUHSC_00069
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Staphylococcus aureus subsp. aureus NCTC 8325 (strain: NCTC 8325, sub-species: aureus)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus
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Genomic context

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Sequence:
NC_007795.1 (73429..74979, complement)

NC_007795.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene L-lactate permease Neighboring gene accessory regulator-like protein Neighboring gene lipoprotein SirC

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007795.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spatial regulation of protein A in Staphylococcus aureus. Zhang R, et al. Mol Microbiol, 2021 Aug. PMID 33949015, Free PMC Article
  2. Temporal Variation in Staphylococcus aureus Protein A Genotypes from Nose and Skin in Atopic Dermatitis Patients. van Mierlo MMF, et al. Dermatology, 2021. PMID 33823508
  3. Protein A of Staphylococcus aureus strain NCTC8325 interacted with heparin. Shi H, et al. Arch Microbiol, 2021 Jul. PMID 33683394
  4. Time-resolved fluorescence resonance energy transfer study shows a compact denatured state of the B domain of protein A. Huang F, et al. Biochemistry, 2009 Apr 21. PMID 19222162
  5. Staphylococcus aureus protein A activates TACE through EGFR-dependent signaling. Gómez MI, et al. EMBO J, 2007 Feb 7. PMID 17255933, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Temporal Variation in Staphylococcus aureus Protein A Genotypes from Nose and Skin in Atopic Dermatitis Patients.
    Title: Temporal Variation in Staphylococcus aureus Protein A Genotypes from Nose and Skin in Atopic Dermatitis Patients.
  2. Spatial regulation of protein A in Staphylococcus aureus.
    Title: Spatial regulation of protein A in Staphylococcus aureus.
  3. Protein A of Staphylococcus aureus strain NCTC8325 interacted with heparin.
    Title: Protein A of Staphylococcus aureus strain NCTC8325 interacted with heparin.
  4. Staphylococcus aureus protein A enhances osteoclastogenesis via TNFR1 and EGFR signaling.
    Title: Staphylococcus aureus protein A enhances osteoclastogenesis via TNFR1 and EGFR signaling.
  5. A two-state folding mechanism of protein A supports the existence of effective nonlocal, probably hydrophobic, intramolecular interactions that stabilize a uniform ensemble of compact denatured molecules at intermediate denaturing conditions.
    Title: Time-resolved fluorescence resonance energy transfer study shows a compact denatured state of the B domain of protein A.
  6. The co-operativity of ultra-fast folding of protein A and whether the Phi-value analysis of its transition state depended on the location of the optical probe, was determined.
    Title: Phi-analysis of the folding of the B domain of protein A using multiple optical probes.
  7. Clumping factor and protein A-negative methicillin resistant S. aureus isolated in Poland do not come from a single clone and the absence of CF and protein A is not caused by the deletion of other genes.
    Title: [Characteristics of clumping factor- and protein A-negative methicillin-resistant Staphylococcus aureus identified in Poland].
  8. Staphylococcus aureus protein A activates TACE through EGFR-dependent signaling.
    Title: Staphylococcus aureus protein A activates TACE through EGFR-dependent signaling.
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General gene information

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Homology

General protein information

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Names
protein A
YP_498670.1
  • protein A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007795.1 Reference assembly

    Range
    73429..74979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_498670.1 protein A [Staphylococcus aureus subsp. aureus NCTC 8325]

    See identical proteins and their annotated locations for YP_498670.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6G4J6R3
    Conserved Domains (4) summary
    cd00118
    Location:422 → 465
    LysM; Lysin Motif is a small domain involved in binding peptidoglycan
    cl30717
    Location:287 → 436
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam02216
    Location:38 → 88
    B; B domain
    pfam04650
    Location:3 → 26
    YSIRK_signal; YSIRK type signal peptide
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02976.3

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