odad4 outer dynein arm docking complex subunit 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: odad4provided by ZNC
Official Full Name: outer dynein arm docking complex subunit 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-995
See related: Ensembl:ENSDARG00000058140 AllianceGenome:ZFIN:ZDB-GENE-040426-995
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ttc25; zgc:56362
Summary: Acts upstream of or within cilium assembly; determination of heart left/right asymmetry; and otolith morphogenesis. Predicted to be located in cell projection and cytoskeleton. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; forerunner cell group; otic placode; pronephric duct; and pronephric mesoderm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 35. Orthologous to human ODAD4 (outer dynein arm docking complex subunit 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (17910569..17928233)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (17760829..17778493)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within cilium assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cilium movement	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within determination of heart left/right asymmetry	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within otolith morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in outer dynein arm assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: outer dynein arm-docking complex subunit 4

Names: TPR repeat protein 25; tetratricopeptide repeat domain 25; tetratricopeptide repeat protein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200316.1 → NP_956610.1 outer dynein arm-docking complex subunit 4

See identical proteins and their annotated locations for NP_956610.1

Status: PROVISIONAL

Source sequence(s)

BC051126

UniProtKB/Swiss-Prot

F1RBQ8, Q7ZU45

Related

ENSDARP00000075390.3, ENSDART00000080946.5

Conserved Domains (3) summary

sd00006
Location:16 → 42

TPR; TPR repeat [structural motif]

pfam13414
Location:16 → 79

TPR_11; TPR repeat

pfam13424
Location:355 → 423

TPR_12; Tetratricopeptide repeat