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amy2al1 amylase alpha 2A-like 1 [ Danio rerio (zebrafish) ]

Gene ID: 393400, updated on 2-Nov-2024

Summary

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Official Symbol
amy2al1provided by ZNC
Official Full Name
amylase alpha 2A-like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1606
See related
Ensembl:ENSDARG00000030357 AllianceGenome:ZFIN:ZDB-GENE-040426-1606
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:66313
Summary
Predicted to enable alpha-amylase activity. Acts upstream of or within cellular response to estrogen stimulus. Predicted to be active in extracellular space. Is expressed in digestive system; endocrine system; gut; lens; and pancreas. Orthologous to human AMY2A (amylase alpha 2A) and AMY2B (amylase alpha 2B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See amy2al1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (43863743..43886997)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (43749948..43773236)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene jumonji domain containing 1Ca Neighboring gene uncharacterized LOC137488137 Neighboring gene dr1-associated corepressor Neighboring gene AHA1, activator of heat shock protein ATPase homolog 1b Neighboring gene uncharacterized LOC137488139 Neighboring gene mutS homolog 4 Neighboring gene kinectin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Exogenous maltose enhances Zebrafish immunity to levofloxacin-resistant Vibrio alginolyticus. Jiang M, et al. Microb Biotechnol, 2020 Jul. PMID 32364684, Free PMC Article
  2. Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology. Lam SH, et al. PLoS Genet, 2008 Jul 11. PMID 18618001, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC66313

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables alpha-amylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha-amylase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables cation binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cellular response to estrogen stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
AmyAc_bac_euk_AmyA and Aamy_C domain-containing protein; amyAc_bac_euk_AmyA and Aamy_C domain-containing protein
NP_956722.2
XP_005158947.1
XP_017207095.1
XP_068070442.1
XP_068070443.1
XP_068070444.1
XP_068070445.1
XP_068070446.1
XP_068070447.1
XP_068070448.1
XP_068070449.1
XP_068070450.1
XP_068070451.1
XP_068070452.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200428.2 → NP_956722.2  AmyAc_bac_euk_AmyA and Aamy_C domain-containing protein precursor

    Status: VALIDATED

    Source sequence(s)
    BX465227
    UniProtKB/TrEMBL
    A0A0R4IST0, A0A8M2B5V6
    Related
    ENSDARP00000112576.1, ENSDART00000134272.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    43863743..43886997
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068214348.1 → XP_068070449.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

  2. XM_068214349.1 → XP_068070450.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

  3. XM_068214351.1 → XP_068070452.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

  4. XM_068214344.1 → XP_068070445.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X1

  5. XM_068214346.1 → XP_068070447.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

  6. XM_068214341.1 → XP_068070442.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X1

  7. XM_068214345.1 → XP_068070446.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

  8. XM_068214350.1 → XP_068070451.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

  9. XM_068214342.1 → XP_068070443.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X1

  10. XM_017351606.3 → XP_017207095.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

    UniProtKB/TrEMBL
    A0A0R4IST0, A0A8M2B5V6, Q7SYK9
    Related
    ENSDARP00000137839.1, ENSDART00000167214.2
    Conserved Domains (3) summary
    cd11317
    Location:25 → 417
    AmyAc_bac_euk_AmyA; Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase)
    smart00632
    Location:424 → 511
    Aamy_C; Aamy_C domain
    COG0366
    Location:46 → 315
    AmyA; Glycosidase [Carbohydrate transport and metabolism]

  11. XM_068214343.1 → XP_068070444.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X1

  12. XM_068214347.1 → XP_068070448.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

  13. XM_005158890.5 → XP_005158947.1  amyAc_bac_euk_AmyA and Aamy_C domain-containing protein isoform X2

    See identical proteins and their annotated locations for XP_005158947.1

    UniProtKB/TrEMBL
    A0A0R4IST0, A0A8M2B5V6, Q7SYK9
    Conserved Domains (3) summary
    cd11317
    Location:25 → 417
    AmyAc_bac_euk_AmyA; Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase)
    smart00632
    Location:424 → 511
    Aamy_C; Aamy_C domain
    COG0366
    Location:46 → 315
    AmyA; Glycosidase [Carbohydrate transport and metabolism]
Nucleotide Protein Strain
Heading Accession and Version

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