U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mtmr4 myotubularin related protein 4 [ Danio rerio (zebrafish) ]

Gene ID: 393584, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
mtmr4provided by ZNC
Official Full Name
myotubularin related protein 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1208
See related
AllianceGenome:ZFIN:ZDB-GENE-040426-1208
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63645
Summary
Predicted to enable metal ion binding activity; phosphatidylinositol-3-phosphate phosphatase activity; and protein tyrosine phosphatase activity. Predicted to act upstream of or within dephosphorylation and lipid metabolic process. Predicted to be located in cytoplasm and membrane. Orthologous to human MTMR4 (myotubularin related protein 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See mtmr4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (2301327..2810348, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (2033113..2540122, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene glucuronidase, beta Neighboring gene uncharacterized LOC137495508 Neighboring gene carbonic anhydrase IV a Neighboring gene uncharacterized LOC103910293 Neighboring gene citron rho-interacting serine/threonine kinase a Neighboring gene RAB35, member RAS oncogene family a Neighboring gene transmembrane protein 127 Neighboring gene Rab9 effector protein with kelch motifs Neighboring gene DDRGK domain-containing protein 1 Neighboring gene leucine zipper putative tumor suppressor 3 Neighboring gene guanine nucleotide binding protein (G protein), gamma 10 Neighboring gene FAST kinase domains 5 Neighboring gene heat shock protein 5 Neighboring gene 4-hydroxyphenylpyruvate dioxygenase a Neighboring gene ring finger protein 43 Neighboring gene uncharacterized LOC137495543

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC63645

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylinositol-3-phosphate phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
myotubularin-related protein 4
Names
myotubularin-related protein 4-like
XP_002667032.4
XP_009299405.1
XP_068077451.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    2301327..2810348 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009301130.4 → XP_009299405.1  myotubularin-related protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A8M3ARV3
    Conserved Domains (3) summary
    cd15733
    Location:1011 → 1070
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    pfam06602
    Location:160 → 513
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:23 → 136
    PH-like; Pleckstrin homology-like domain

  2. XM_002666986.7 → XP_002667032.4  myotubularin-related protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8M1RI73
    Conserved Domains (3) summary
    cd15733
    Location:1023 → 1082
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    pfam06602
    Location:172 → 525
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:35 → 148
    PH-like; Pleckstrin homology-like domain

  3. XM_068221350.1 → XP_068077451.1  myotubularin-related protein 4 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_200612.1: Suppressed sequence

    Description
    NM_200612.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools