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pdcd6 programmed cell death 6 [ Danio rerio (zebrafish) ]

Gene ID: 393925, updated on 4-Jan-2025

Summary

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Official Symbol
pdcd6provided by ZNC
Official Full Name
programmed cell death 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1307
See related
Ensembl:ENSDARG00000005220 AllianceGenome:ZFIN:ZDB-GENE-040426-1307
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63952
Summary
Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to be located in cytoplasm. Is expressed in notochord; pectoral fin cartilage; and pharyngeal arch 3-7 skeleton. Orthologous to human PDCD6 (programmed cell death 6). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See pdcd6 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (12629649..12689545, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (12483355..12543251, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene G2/M phase-specific E3 ubiquitin-protein ligase Neighboring gene uncharacterized LOC137489220 Neighboring gene uncharacterized LOC137489219 Neighboring gene si:ch211-196f5.2 Neighboring gene REC8 meiotic recombination protein b Neighboring gene cytochrome c oxidase assembly factor COX19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22. Montaville P, et al. Biochim Biophys Acta, 2006 Nov. PMID 17045351
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC63952

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-dependent protein binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
programmed cell death protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200950.1 → NP_957244.1  programmed cell death protein 6

    See identical proteins and their annotated locations for NP_957244.1

    Status: PROVISIONAL

    Source sequence(s)
    BC053162
    UniProtKB/TrEMBL
    A0A8M1PC11, Q7T3D5
    Related
    ENSDARP00000009990.5, ENSDART00000015517.6
    Conserved Domains (1) summary
    cd16183
    Location:21 → 185
    EFh_PEF_ALG-2; EF-hand, calcium binding motif, found in apoptosis-linked gene 2 protein (ALG-2) and similar proteins

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    12629649..12689545 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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