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surf6 surfeit 6 [ Danio rerio (zebrafish) ]

Gene ID: 394040, updated on 2-Nov-2024

Summary

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Official Symbol
surf6provided by ZNC
Official Full Name
surfeit 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1333
See related
Ensembl:ENSDARG00000035427 AllianceGenome:ZFIN:ZDB-GENE-040426-1333
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
surf6l; zgc:64008
Summary
Acts upstream of or within heart development. Predicted to be located in nucleus. Is expressed in several structures, including alar plate midbrain region; immature eye; midbrain; retina; and segmental plate. Orthologous to human SURF6 (surfeit 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See surf6 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (33275151..33281122, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (32675000..32680928, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene interferon induced transmembrane protein 1 Neighboring gene kynurenine aminotransferase 1 Neighboring gene SURF1 cytochrome c oxidase assembly factor Neighboring gene small nucleolar RNA SNORD36 Neighboring gene ribosomal protein L7a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Milan DJ, et al. Circulation, 2009 Aug 18. PMID 19652097, Free PMC Article
  2. Evolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular development. Hensley MR, et al. Sci Rep, 2016 Jun 13. PMID 27292017, Free PMC Article
  3. ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis. Krens SF, et al. BMC Genomics, 2008 Apr 28. PMID 18442396, Free PMC Article
  4. Positive correlation between gene coexpression and positional clustering in the zebrafish genome. Ng YK, et al. BMC Genomics, 2009 Jan 22. PMID 19159490, Free PMC Article
  5. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC64008

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
surfeit locus protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201065.1 → NP_957359.1  surfeit locus protein 6

    See identical proteins and their annotated locations for NP_957359.1

    Status: PROVISIONAL

    Source sequence(s)
    BC053193
    UniProtKB/TrEMBL
    Q7T3A6
    Related
    ENSDARP00000051343.5, ENSDART00000051344.6
    Conserved Domains (1) summary
    pfam04935
    Location:194 → 350
    SURF6; Surfeit locus protein 6

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    33275151..33281122 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171804.5 → XP_005171861.1  surfeit locus protein 6 isoform X1

    See identical proteins and their annotated locations for XP_005171861.1

    UniProtKB/TrEMBL
    A0A8M2BJL3, Q6DRK9
    Related
    ENSDARP00000121048.1, ENSDART00000138116.3
    Conserved Domains (1) summary
    pfam04935
    Location:194 → 350
    SURF6; Surfeit locus protein 6
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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