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homer3b homer scaffold protein 3b [ Danio rerio (zebrafish) ]

Gene ID: 394088, updated on 2-Nov-2024

Summary

Official Symbol
homer3bprovided by ZNC
Official Full Name
homer scaffold protein 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-739
See related
Ensembl:ENSDARG00000010789 AllianceGenome:ZFIN:ZDB-GENE-040426-739
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
homer3; zgc:55557
Summary
Predicted to enable G protein-coupled glutamate receptor binding activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of store-operated calcium entry. Predicted to be located in synapse. Predicted to be active in several cellular components, including dendrite; plasma membrane; and postsynaptic density. Orthologous to human HOMER3 (homer scaffold protein 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See homer3b in Genome Data Viewer
Location:
chromosome: 11
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (13424194..13505660)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (13366579..13447995)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene microtubule associated serine/threonine kinase 3b Neighboring gene interleukin 12 receptor subunit beta 1 Neighboring gene uncharacterized LOC137496676 Neighboring gene si:dkey-13m1.5 Neighboring gene arrestin domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC55557

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled glutamate receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G protein-coupled glutamate receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled glutamate receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within G protein-coupled glutamate receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of store-operated calcium entry IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
homer protein homolog 3b
Names
homer homolog 3
homer scaffolding protein 3
homer scaffolding protein 3b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201113.1NP_957407.1  homer protein homolog 3b

    See identical proteins and their annotated locations for NP_957407.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045383
    UniProtKB/TrEMBL
    Q7ZVW5
    Related
    ENSDARP00000106317.2, ENSDART00000125563.3
    Conserved Domains (2) summary
    cd01206
    Location:3111
    EVH1_Homer_Vesl; Homer/Vesl family proteins EVH1 domain
    pfam12269
    Location:279327
    zf-CpG_bind_C; CpG binding protein zinc finger C terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    13424194..13505660
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068224131.1XP_068080232.1  homer protein homolog 3b isoform X1

    Related
    ENSDARP00000093329.5, ENSDART00000102553.5
  2. XM_068224132.1XP_068080233.1  homer protein homolog 3b isoform X2