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e2f5 - E2F transcription factor 5

Enables DNA-binding transcription factor activity. Acts upstream of or within female somatic sex determination; male meiosis I; and multi-ciliated epithelial cell differentiation. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human E2F5 (E2F transcription factor 5). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa