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Or8k36-ps1 olfactory receptor family 8 subfamily K member 36, pseudogene 1 [ Mus musculus (house mouse) ]

Gene ID: 404326, updated on 17-Aug-2024

Summary

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Official Symbol
Or8k36-ps1provided by MGI
Official Full Name
olfactory receptor family 8 subfamily K member 36, pseudogene 1provided by MGI
Primary source
MGI:MGI:3030917
See related
Ensembl:ENSMUSG00000068824 AllianceGenome:MGI:3030917
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR191-3; Olfr1083; Olfr1083-ps
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the non-coding allele. [provided by RefSeq, Apr 2024]
Annotation information
Annotation category: suggests misassembly
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Note: This locus likely represents a polymorphic pseudogene. The open reading frame is disrupted by a 1-nt insertion in the C57BL/6J reference assembly, but appears to be intact in other strains, such as A/J. [15 Jul 2011]
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Genomic context

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Location:
2 D; 2 49.85 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (86436971..86437913, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (86606627..86607569, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily K member 34, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_05030 Neighboring gene olfactory receptor family 8 subfamily K member 35 Neighboring gene olfactory receptor family 8 subfamily K member 37 Neighboring gene olfactory receptor family 8 subfamily K member 38

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
  2. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  3. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  4. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  5. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

General protein information

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Preferred Names
olfactory receptor family 8 subfamily K member 36, pseudogene 1
Names
GA_x6K02T2Q125-48092599-48091658
olfactory receptor 1083, pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001429717.1 → NP_001416646.1  olfactory receptor family 8 subfamily K member 36, pseudogene 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (coding) represents the functional allele that is not present in some strains, including the strain of the reference genome.
    Source sequence(s)
    OW971784
    UniProtKB/TrEMBL
    Q7TR66

RNA

  1. NR_190775.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (non-coding) has an indel that introduces a frameshift and premature stop codon. It represents the non-functional allele present in some strains, including the strain of the reference genome.
    Source sequence(s)
    AL772265, BX294651

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    86436971..86437913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_029460.1: Suppressed sequence

    Description
    NG_029460.1: This RefSeq was removed by NCBI staff.

  2. NM_207564.2: Suppressed sequence

    Description
    NM_207564.2: This RefSeq was permanently suppressed because it appears to be a pseudogene in C57BL/6.
Nucleotide Protein Strain
Heading Accession and Version

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