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rbm4.3 RNA binding motif protein 4.3 [ Danio rerio (zebrafish) ]

Gene ID: 406277, updated on 14-Nov-2024

Summary

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Official Symbol
rbm4.3provided by ZNC
Official Full Name
RNA binding motif protein 4.3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1938
See related
Ensembl:ENSDARG00000022129 AllianceGenome:ZFIN:ZDB-GENE-040426-1938
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb55c03; fb78a04; fj36h04; zgc:56141; zgc:77000; wu:fb55c03; wu:fb78a04; wu:fj36h04
Summary
Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be active in nuclear speck. Orthologous to human RBM4 (RNA binding motif protein 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See rbm4.3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (22792132..22795639)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (22520933..22524480)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene TRAF interacting protein with forkhead associated domain Neighboring gene RNA binding motif protein 4.2 Neighboring gene RNA binding motif protein 4.1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Phylogenetic and molecular characterization of the splicing factor RBM4. Lu CC, et al. PLoS One, 2013. PMID 23527094, Free PMC Article
  2. RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation. Rösel TD, et al. EMBO J, 2011 May 18. PMID 21468032, Free PMC Article
  3. Proteomic profile of zebrafish brain based on two-dimensional gel electrophoresis matrix-assisted laser desorption/ionization MS/MS analysis. Singh SK, et al. Zebrafish, 2010 Jun. PMID 20528263
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA-binding protein 4.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213317.3 → NP_998482.1  RNA-binding protein 4.3

    See identical proteins and their annotated locations for NP_998482.1

    Status: VALIDATED

    Source sequence(s)
    AL928799
    UniProtKB/TrEMBL
    A0A8M1PJ67, Q6NXC1
    Related
    ENSDARP00000117497.1, ENSDART00000135207.3
    Conserved Domains (1) summary
    cl17169
    Location:2 → 68
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    22792132..22795639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068222208.1 → XP_068078309.1  RNA-binding protein 4.3 isoform X1

  2. XM_068222207.1 → XP_068078308.1  RNA-binding protein 4.3 isoform X1

    Related
    ENSDARP00000148114.1, ENSDART00000184407.1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_213004.1: Suppressed sequence

    Description
    NM_213004.1: This RefSeq was permanently suppressed because there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version

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