cyp20a1 cytochrome P450, family 20, subfamily A, polypeptide 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cyp20a1provided by ZNC
Official Full Name: cytochrome P450, family 20, subfamily A, polypeptide 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2646
See related: Ensembl:ENSDARG00000006040 AllianceGenome:ZFIN:ZDB-GENE-040426-2646
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:63986; wu:fa10c06
Summary: Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Acts upstream of or within optomotor response and swimming behavior. Predicted to be located in membrane. Is expressed in female organism; male organism; and notochord. Orthologous to human CYP20A1 (cytochrome P450 family 20 subfamily A member 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (9951960..9969463)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (9717098..9733919)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Orphan cytochrome P450 20a1 CRISPR/Cas9 mutants and neurobehavioral phenotypes in zebrafish.
Title: Orphan cytochrome P450 20a1 CRISPR/Cas9 mutants and neurobehavioral phenotypes in zebrafish.

Submit: New GeneRIF Correction

General gene information

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Markers

fa10c06.s1 (e-PCR)
- UniSTS:202278

aa494577 (e-PCR)
- UniSTS:186785

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within optomotor response	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within swimming behavior	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome P450 20A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213332.2 → NP_998497.2 cytochrome P450 20A1

Status: VALIDATED

Source sequence(s)

CU929158, EH508788, EH530312

UniProtKB/TrEMBL

A0A8M1PPN0, F1QHW0

Related

ENSDARP00000003222.7, ENSDART00000019325.9

Conserved Domains (1) summary

cl12078
Location:43 → 452

p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

9951960..9969463

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021476831.2 → XP_021332506.1 cytochrome P450 20A1 isoform X1

UniProtKB/TrEMBL

A0A8M9QAA0

Conserved Domains (1) summary

cl12078
Location:35 → 350

p450; Cytochrome P450