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tmem129 transmembrane protein 129, E3 ubiquitin protein ligase [ Danio rerio (zebrafish) ]

Gene ID: 406756, updated on 2-Nov-2024

Summary

Official Symbol
tmem129provided by ZNC
Official Full Name
transmembrane protein 129, E3 ubiquitin protein ligaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2796
See related
Ensembl:ENSDARG00000075346 AllianceGenome:ZFIN:ZDB-GENE-040426-2796
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc17d07; zgc:63798; wu:fc17d07; wu:fc37f02; wu:fk28c04
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within response to unfolded protein. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human TMEM129 (transmembrane protein 129, E3 ubiquitin ligase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See tmem129 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (9581896..9588317)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (9275882..9282303)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene si:zfos-2326c3.2 Neighboring gene uncharacterized LOC100329833 Neighboring gene atonal bHLH transcription factor 8 Neighboring gene interleukin 1 receptor accessory protein-like 2 Neighboring gene uncharacterized LOC103912066

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to unfolded protein IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
E3 ubiquitin-protein ligase TM129
Names
RING-type E3 ubiquitin transferase TM129
NP_998612.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213447.1NP_998612.1  E3 ubiquitin-protein ligase TM129

    See identical proteins and their annotated locations for NP_998612.1

    Status: PROVISIONAL

    Source sequence(s)
    BC058876
    UniProtKB/Swiss-Prot
    Q6PD82
    Related
    ENSDARP00000101988.3, ENSDART00000114563.4
    Conserved Domains (1) summary
    pfam10272
    Location:17358
    Tmpp129; Putative transmembrane protein precursor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    9581896..9588317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)