tax1bp3 Tax1 (human T-cell leukemia virus type I) binding protein 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tax1bp3provided by ZNC
Official Full Name: Tax1 (human T-cell leukemia virus type I) binding protein 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2830
See related: Ensembl:ENSDARG00000059177 AllianceGenome:ZFIN:ZDB-GENE-040426-2830
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55513; wu:fb37e03; wu:fc23g08
Summary: Acts upstream of or within convergent extension involved in axis elongation. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in nucleus. Is expressed in brain; eye; heart; and immature eye. Orthologous to human TAX1BP3 (Tax1 binding protein 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 11

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (6136260..6145158)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (6139005..6147903)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

observations indicate a role for TIP-1 in gastrulation movements and in filopodia growth induction
Title: Tip-1 induces filopodia growth and is important for gastrulation movements during zebrafish development.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fa10d03.s1 (e-PCR)
- UniSTS:202279

fb37e03.x1 (e-PCR)
- UniSTS:190524

fc23g08.x1 (e-PCR)
- UniSTS:193165

tip1 (e-PCR)
- UniSTS:205486

fc23g08.x1 (e-PCR)
- UniSTS:187845

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within Wnt signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in Wnt signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within convergent extension involved in axis elongation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: tax1-binding protein 3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213470.1 → NP_998635.1 tax1-binding protein 3

See identical proteins and their annotated locations for NP_998635.1

Status: PROVISIONAL

Source sequence(s)

BC042322

UniProtKB/TrEMBL

A0A8M1PJH3, Q8AWD4

Related

ENSDARP00000076660.3, ENSDART00000082223.4

Conserved Domains (1) summary

cd00992
Location:13 → 109

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...