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sdr16c5b short chain dehydrogenase/reductase family 16C, member 5b [ Danio rerio (zebrafish) ]

Gene ID: 406799, updated on 2-Nov-2024

Summary

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Official Symbol
sdr16c5bprovided by ZNC
Official Full Name
short chain dehydrogenase/reductase family 16C, member 5bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2861
See related
Ensembl:ENSDARG00000017794 AllianceGenome:ZFIN:ZDB-GENE-040426-2861
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rdhe2; sdr16c5; zgc:63829; wu:fj05d06
Summary
Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be active in lipid droplet. Is expressed in liver. Orthologous to human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human all
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Genomic context

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See sdr16c5b in Genome Data Viewer
Location:
chromosome: 7
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (58699745..58718472)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (58397305..58416032)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496227 Neighboring gene proenkephalin b Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 7 Neighboring gene pleiomorphic adenoma gene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A zebrafish cell culture assay for the identification of microRNA targets. Liu W, et al. Zebrafish, 2010 Dec. PMID 21158564, Free PMC Article
  2. Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish. Bazzini AA, et al. Science, 2012 Apr 13. PMID 22422859, Free PMC Article
  3. RESA identifies mRNA-regulatory sequences at high resolution. Yartseva V, et al. Nat Methods, 2017 Feb. PMID 28024160, Free PMC Article
  4. Identification and expression of liver-specific genes after LPS challenge in amphioxus: the hepatic cecum as liver-like organ and "pre-hepatic" acute phase response. Wang Y, et al. Funct Integr Genomics, 2011 Mar. PMID 21052758
  5. Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition. Du Z, et al. Biochem Biophys Res Commun, 2016 Jun 24. PMID 27235108

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables all-trans-retinol dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in lipid droplet IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
epidermal retinol dehydrogenase 2
Names
epidermal retinal dehydrogenase 2
short chain dehydrogenase/reductase family 16C, member 5
NP_999936.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214771.2 → NP_999936.1  epidermal retinol dehydrogenase 2

    See identical proteins and their annotated locations for NP_999936.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054138
    UniProtKB/TrEMBL
    A0A8M1PFP2, Q7SZ49
    Related
    ENSDARP00000049263.5, ENSDART00000049264.7
    Conserved Domains (2) summary
    cd05339
    Location:38 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
    pfam00106
    Location:39 → 233
    adh_short; short chain dehydrogenase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    58699745..58718472
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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