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Obp99a Odorant-binding protein 99a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43488, updated on 18-Sep-2024

Summary

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Official Symbol
Obp99aprovided by FlyBase
Official Full Name
Odorant-binding protein 99aprovided by FlyBase
Primary source
FLYBASE:FBgn0039678
Locus tag
Dmel_CG18111
See related
AllianceGenome:FB:FBgn0039678
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
99a; BcDNA:RH70762; CG18111; DmelObp99a; Dmel\CG18111; obp99a; OBP99a; OBP99A
Summary
Predicted to enable odorant binding activity. Predicted to be involved in olfactory behavior; response to pheromone; and sensory perception of smell. Located in endomembrane system. Is expressed in ectoderm; embryonic antennal sense organ; extended germ band embryo; and presumptive embryonic/larval system. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Obp99a in Genome Data Viewer
Location:
99B7-99B7; 3-99 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29671657..29672334)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25497379..25498056)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pickpocket 20 Neighboring gene pickpocket 30 Neighboring gene pickpocket 19 Neighboring gene Bub3 Neighboring gene CAP-D2 condensin subunit Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural variation in odorant recognition among odorant-binding proteins in Drosophila melanogaster. Wang P, et al. Genetics, 2010 Mar. PMID 20026676, Free PMC Article
  2. Proteome profiling reveals tissue-specific protein expression in the male reproductive system of Drosophila melanogaster. Yamamoto MT, et al. Fly (Austin), 2010 Jan-Mar. PMID 20139713
  3. The invertebrate odorant-binding protein LUSH is required for normal olfactory behavior in Drosophila. Kim MS, et al. Chem Senses, 2001 Feb. PMID 11238251
  4. Conservation of the behavioral and transcriptional response to social experience among Drosophilids. Shultzaberger RK, et al. Genes Brain Behav, 2019 Jan. PMID 29797548, Free PMC Article
  5. Stochastic Modeling of Gene Expression Evolution Uncovers Tissue- and Sex-Specific Properties of Expression Evolution in the Drosophila Genus. Pal S, et al. J Comput Biol, 2023 Jan. PMID 36037023, Free PMC Article

See all (71) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables odorant binding NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in olfactory behavior ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in response to pheromone ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 
located_in extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Odorant-binding protein 99a
Names
CG18111-PA
CG18111-PB
Obp99a-PA
Obp99a-PB
odorant binding protein 99a

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    29671657..29672334
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143450.3 → NP_651707.1  Odorant-binding protein 99a, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651707.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A9QIH3, A9QII9, A9QIJ4, A9QIU5, Q9VAJ4
    UniProtKB/TrEMBL
    D1FYH5, D1FYI8, D1FYJ0, D1FYR1
    Related
    FBpp0084816
    Conserved Domains (1) summary
    smart00708
    Location:29 → 130
    PhBP; Insect pheromone/odorant binding protein domains

  2. NM_001300657.1 → NP_001287586.1  Odorant-binding protein 99a, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287586.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A9QIH3, A9QII9, A9QIJ4, A9QIU5, Q9VAJ4
    UniProtKB/TrEMBL
    D1FYH5, D1FYI8, D1FYJ0, D1FYR1
    Conserved Domains (1) summary
    smart00708
    Location:29 → 130
    PhBP; Insect pheromone/odorant binding protein domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D1FYH5 D1FYH5
Q9VAJ4.2 Q9VAJ4

Gene LinkOut

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