txnb thioredoxin b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: txnbprovided by ZNC
Official Full Name: thioredoxin bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-162
See related: Ensembl:ENSDARG00000044125 AllianceGenome:ZFIN:ZDB-GENE-040718-162
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: txn; zgc:92903
Summary: Predicted to enable protein-disulfide reductase activity. Predicted to act upstream of or within cell redox homeostasis and glycerol ether metabolic process. Is expressed in liver; nervous system; spinal cord neural tube; and yolk syncytial layer. Orthologous to several human genes including TXN (thioredoxin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (24357231..24364504, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (24086074..24093347, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein-disulfide reductase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: thioredoxin b

Names: TXN1; thioredoxin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002461.1 → NP_001002461.1 thioredoxin b

See identical proteins and their annotated locations for NP_001002461.1

Status: PROVISIONAL

Source sequence(s)

BC076358

UniProtKB/TrEMBL

B2GPR1, Q6DGI6

Related

ENSDARP00000064788.2, ENSDART00000064789.3

Conserved Domains (1) summary

cd02947
Location:9 → 104

TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...