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rpl35a ribosomal protein L35a [ Danio rerio (zebrafish) ]

Gene ID: 436760, updated on 2-Nov-2024

Summary

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Official Symbol
rpl35aprovided by ZNC
Official Full Name
ribosomal protein L35aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-190
See related
Ensembl:ENSDARG00000088030 AllianceGenome:ZFIN:ZDB-GENE-040718-190
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92859
Summary
Predicted to be a structural constituent of ribosome. Acts upstream of or within chordate embryonic development and erythrocyte differentiation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in endodermal cell; intestine; liver; and pancreas. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5. Orthologous to human RPL35A (ribosomal protein L35a). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See rpl35a in Genome Data Viewer
Location:
chromosome: 18
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (45781232..45788657)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (45784406..45791831)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC606627 Neighboring gene si:dkey-34o23.3 Neighboring gene ATP-binding cassette, sub-family C (CFTR/MRP), member 5 Neighboring gene arginyl aminopeptidase like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish. Yadav GV, et al. Int J Biochem Cell Biol, 2014 Apr. PMID 24417973
  2. Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish. Chen LT, et al. Nat Commun, 2014 May 2. PMID 24787902
  3. Serial analysis of gene expression in the skeletal muscles of zebrafish fed with a methylmercury-contaminated diet. Cambier S, et al. Environ Sci Technol, 2010 Jan 1. PMID 20039754
  4. Ribosomal protein gene knockdown causes developmental defects in zebrafish. Uechi T, et al. PLoS One, 2006 Dec 20. PMID 17183665, Free PMC Article
  5. Multiple ribosomal proteins are expressed at high levels in developing zebrafish endoderm and are required for normal exocrine pancreas development. Provost E, et al. Zebrafish, 2013 Jun. PMID 23697888, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chordate embryonic development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein eL33

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002487.1 → NP_001002487.1  large ribosomal subunit protein eL33

    See identical proteins and their annotated locations for NP_001002487.1

    Status: PROVISIONAL

    Source sequence(s)
    BC076321
    UniProtKB/TrEMBL
    A0A8M1N0G8, F1QE85, I3ITJ0, Q6DGM0
    Related
    ENSDARP00000155179.1, ENSDART00000179887.1
    Conserved Domains (1) summary
    pfam01247
    Location:5 → 103
    Ribosomal_L35Ae; Ribosomal protein L35Ae

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    45781232..45788657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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