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rnf144ab ring finger protein 144ab [ Danio rerio (zebrafish) ]

Gene ID: 437000, updated on 2-Nov-2024

Summary

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Official Symbol
rnf144abprovided by ZNC
Official Full Name
ring finger protein 144abprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-486
See related
Ensembl:ENSDARG00000042557 AllianceGenome:ZFIN:ZDB-GENE-040718-486
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rnf144; rnf144a; zgc:92582; wu:fj49a04; si:dkeyp-7f8.1-001
Summary
Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within protein ubiquitination. Predicted to be located in membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in Golgi apparatus. Orthologous to human RNF144A (ring finger protein 144A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See rnf144ab in Genome Data Viewer
Location:
chromosome: 20
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (29836276..29864568, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (29933397..29961679, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488586 Neighboring gene inhibitor of DNA binding 2b Neighboring gene SRY-box transcription factor 11b Neighboring gene uncharacterized LOC101884038

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafish. Postlethwait JH, et al. Biol Open, 2021 Mar 23. PMID 33757938, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin conjugating enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
probable E3 ubiquitin-protein ligase RNF144A-B
Names
RING finger protein 144A-B
ring finger protein 144
ring finger protein 144a
NP_001002727.1
XP_005160733.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002727.1 → NP_001002727.1  probable E3 ubiquitin-protein ligase RNF144A-B

    See identical proteins and their annotated locations for NP_001002727.1

    Status: PROVISIONAL

    Source sequence(s)
    BC076084
    UniProtKB/Swiss-Prot
    Q5TZ96, Q6DH94
    Related
    ENSDARP00000140429.2, ENSDART00000161834.2
    Conserved Domains (2) summary
    smart00647
    Location:93 → 156
    IBR; In Between Ring fingers
    pfam01485
    Location:178 → 217
    IBR; IBR domain, a half RING-finger domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    29836276..29864568 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005160676.5 → XP_005160733.1  probable E3 ubiquitin-protein ligase RNF144A-B isoform X1

    UniProtKB/TrEMBL
    A0A8M2B7K6, Z4YIB5
    Related
    ENSDARP00000112931.1, ENSDART00000132278.4
    Conserved Domains (2) summary
    smart00647
    Location:93 → 156
    IBR; In Between Ring fingers
    pfam01485
    Location:179 → 218
    IBR; IBR domain, a half RING-finger domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6DH94.1 GenPept UniProtKB/Swiss-Prot:Q6DH94

Gene LinkOut

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