Mcr - Macroglobulin complement-related

Enables structural molecule activity. Involved in several processes, including embryonic development via the syncytial blastoderm; regulation of tube length, open tracheal system; and septate junction assembly. Located in several cellular components, including apicolateral plasma membrane; basolateral plasma membrane; and lateral plasma membrane. Is expressed in several structures, including embryonic/larval plasmatocyte; gut section; mesothoracic phragma; presumptive embryonic/larval system; and testis. Human ortholog(s) of this gene implicated in several diseases, including complement component 5 deficiency; liver cirrhosis; neutropenia; paroxysmal nocturnal hemoglobinuria; and pneumonia. Orthologous to human C5 (complement C5). [provided by Alliance of Genome Resources, Apr 2022]

NCBI Orthologs

How was this calculated?