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gpn1 GPN-loop GTPase 1 [ Danio rerio (zebrafish) ]

Gene ID: 445239, updated on 2-Nov-2024

Summary

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Official Symbol
gpn1provided by ZNC
Official Full Name
GPN-loop GTPase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-154
See related
Ensembl:ENSDARG00000043928 AllianceGenome:ZFIN:ZDB-GENE-040801-154
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:100927
Summary
Predicted to enable GTPase activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human GPN1 (GPN-loop GTPase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See gpn1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (12658435..12675267)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (12504369..12521201)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene zinc finger CCHC domain-containing protein 18-like Neighboring gene elastin microfibril interfacer 1b Neighboring gene uncharacterized LOC101886086 Neighboring gene stathmin-like 4, like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GPN-loop GTPase 1
NP_001003633.1
XP_068070489.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003633.1 → NP_001003633.1  GPN-loop GTPase 1

    See identical proteins and their annotated locations for NP_001003633.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078195
    UniProtKB/TrEMBL
    Q6DC83
    Related
    ENSDARP00000121489.1, ENSDART00000139918.2
    Conserved Domains (2) summary
    COG1100
    Location:1 → 203
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam03029
    Location:1 → 239
    ATP_bind_1; Conserved hypothetical ATP binding protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    12658435..12675267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068214388.1 → XP_068070489.1  GPN-loop GTPase 1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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