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fkbp2 FKBP prolyl isomerase 2 [ Danio rerio (zebrafish) ]

Gene ID: 447939, updated on 4-Jan-2025

Summary

Official Symbol
fkbp2provided by ZNC
Official Full Name
FKBP prolyl isomerase 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040912-126
See related
Ensembl:ENSDARG00000044540 AllianceGenome:ZFIN:ZDB-GENE-040912-126
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101826
Summary
Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to act upstream of or within chaperone-mediated protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in endoplasmic reticulum. Orthologous to human FKBP2 (FKBP prolyl isomerase 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See fkbp2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (26991196..26996037)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (26954501..26959342)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene pyruvate carboxylase a Neighboring gene uncharacterized LOC101883097 Neighboring gene uncharacterized LOC101883049 Neighboring gene leucine rich repeat and fibronectin type III domain containing 4a Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14Ba Neighboring gene solute carrier family 8 member 4a Neighboring gene BCL2 associated agonist of cell death a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidyl-prolyl cis-trans isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within chaperone-mediated protein folding IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein peptidyl-prolyl isomerization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
peptidyl-prolyl cis-trans isomerase FKBP2
Names
FK506 binding protein 2
NP_001004677.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004677.2NP_001004677.2  peptidyl-prolyl cis-trans isomerase FKBP2 precursor

    See identical proteins and their annotated locations for NP_001004677.2

    Status: VALIDATED

    Source sequence(s)
    BX465183, EH538052, EH560251
    UniProtKB/TrEMBL
    A0A8M1N2D2, A9JSW0
    Related
    ENSDARP00000065396.4, ENSDART00000065397.6
    Conserved Domains (1) summary
    pfam00254
    Location:38130
    FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    26991196..26996037
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)