gpd1l glycerol-3-phosphate dehydrogenase 1 like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gpd1lprovided by ZNC
Official Full Name: glycerol-3-phosphate dehydrogenase 1 likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041010-220
See related: Ensembl:ENSDARG00000040024 AllianceGenome:ZFIN:ZDB-GENE-041010-220
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92580; wu:fi13g03; wu:fi45b08
Summary: Predicted to enable NAD binding activity; glycerol-3-phosphate dehydrogenase (NAD+) activity; and protein homodimerization activity. Predicted to act upstream of or within carbohydrate metabolic process and glycerol-3-phosphate catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Orthologous to human GPD1L (glycerol-3-phosphate dehydrogenase 1 like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (39247645..39267233, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (39297613..39317207, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables glycerol-3-phosphate dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
NOT enables glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
NOT involved_in NADH oxidation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glycerol-3-phosphate catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glycerol-3-phosphate metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: glycerol-3-phosphate dehydrogenase 1-like protein

NP_001005934.1

EC 1.1.1.8

XP_068070044.1

EC 1.1.1.8

XP_068070045.1

EC 1.1.1.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005934.2 → NP_001005934.1 glycerol-3-phosphate dehydrogenase 1-like protein

See identical proteins and their annotated locations for NP_001005934.1

Status: VALIDATED

Source sequence(s)

CR848829, CR925805

UniProtKB/Swiss-Prot

Q5XIZ6

Related

ENSDARP00000123149.2, ENSDART00000133642.4

Conserved Domains (3) summary

TIGR03376
Location:6 → 344

glycerol3P_DH; glycerol-3-phosphate dehydrogenase (NAD(+))

pfam01210
Location:6 → 170

NAD_Gly3P_dh_N; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus

pfam07479
Location:197 → 338

NAD_Gly3P_dh_C; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007127.7 Reference GRCz11 Primary Assembly

Range

39247645..39267233 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068213944.1 → XP_068070045.1 glycerol-3-phosphate dehydrogenase 1-like protein isoform X1
XM_068213943.1 → XP_068070044.1 glycerol-3-phosphate dehydrogenase 1-like protein isoform X1