GABRQ gamma-aminobutyric acid type A receptor subunit theta [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: GABRQprovided by VGNC
Official Full Name: gamma-aminobutyric acid type A receptor subunit thetaprovided by VGNC
Primary source: VGNC:VGNC:41066
See related: Ensembl:ENSCAFG00845021121
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	X	NC_051843.1 (122830162..122852448)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	X	NC_006621.4 (105986731..106009002)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	X	NC_049260.1 (121914807..121937084)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	X	NC_049299.1 (119549100..119571365)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	X	NC_049780.1 (122039877..122062152)

Chromosome X - NC_051843.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GABA-A receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables extracellular ligand-gated monoatomic ion channel activity	IEA Inferred from Electronic Annotation more info	PubMed
enables neurotransmitter receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed
involved_in monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nervous system process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of membrane potential	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of GABA-A receptor complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in neuron projection	IEA Inferred from Electronic Annotation more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: gamma-aminobutyric acid receptor subunit theta

Names: gamma-aminobutyric acid (GABA) receptor, theta; gamma-aminobutyric acid type A receptor theta subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051843.1 Reference ROS_Cfam_1.0

Range

122830162..122852448

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038451168.1 → XP_038307096.1 gamma-aminobutyric acid receptor subunit theta

UniProtKB/TrEMBL

A0A8C0LK06, A0A8C0ND37, A0A8I3P6Y4

Related

ENSCAFP00845029181.1, ENSCAFT00845037261.1

Conserved Domains (3) summary

cd19003
Location:82 → 264

LGIC_ECD_GABAAR_theta; extracellular domain of gamma-aminobutyric acid receptor subunit theta (GABRQ)

cd03559
Location:267 → 290

LGIC_TM; TM1 helix [structural motif]

cl38911
Location:267 → 355

LGIC_TM; transmembrane domain of Cys-loop neurotransmitter-gated ion channels

Alternate UMICH_Zoey_3.1

Genomic

NC_049299.1 Alternate UMICH_Zoey_3.1

Range

119549100..119571365

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038524642.1 → XP_038380570.1 gamma-aminobutyric acid receptor subunit theta

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049780.1 Alternate UNSW_CanFamBas_1.0

Range

122039877..122062152

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038653117.1 → XP_038509045.1 gamma-aminobutyric acid receptor subunit theta

Conserved Domains (3) summary

cd19003
Location:82 → 264

LGIC_ECD_GABAAR_theta; extracellular domain of gamma-aminobutyric acid receptor subunit theta (GABRQ)

cd03559
Location:267 → 290

LGIC_TM; TM1 helix [structural motif]

cl38911
Location:267 → 355

LGIC_TM; transmembrane domain of Cys-loop neurotransmitter-gated ion channels

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049260.1 Alternate UU_Cfam_GSD_1.0

Range

121914807..121937084

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038588615.1 → XP_038444543.1 gamma-aminobutyric acid receptor subunit theta

UniProtKB/TrEMBL

A0A8C0LK06, A0A8C0SPU1, A0A8P0SNA3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

105986731..106009002

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_014111996.3 → XP_013967471.1 gamma-aminobutyric acid receptor subunit theta

UniProtKB/TrEMBL

A0A8C0LK06, A0A8C0SPU1, A0A8P0SNA3

Conserved Domains (1) summary

cl27321
Location:61 → 353

Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain