fbxo44.1 F-box protein 44, tandem duplicate 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fbxo44.1provided by ZNC
Official Full Name: F-box protein 44, tandem duplicate 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041212-85
See related: Ensembl:ENSDARG00000022623 AllianceGenome:ZFIN:ZDB-GENE-041212-85
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fbxo44; zgc:92285; wu:fa08a01; wu:fb70d05
Summary: Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in ERAD pathway; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and glycoprotein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to several human genes including FBXO44 (F-box protein 44). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (16748806..16757755)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (16822463..16831412)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

fb70d05.x1 (e-PCR)
- UniSTS:191023

AA542605 (e-PCR)
- UniSTS:206920

fb70d05 (e-PCR)
- UniSTS:187372

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
contributes_to ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ERAD pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in glycoprotein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of SCF ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: F-box only protein 44

Names: F-box protein 44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008577.2 → NP_001008577.2 F-box only protein 44

Status: VALIDATED

Source sequence(s)

AL732515, BC086967, EH586784

UniProtKB/TrEMBL

A0A8M1N3I3, F1QSL6, Q5PQY7

Related

ENSDARP00000122089.1, ENSDART00000137737.3

Conserved Domains (2) summary

smart00256
Location:50 → 90

FBOX; A Receptor for Ubiquitination Targets

pfam04300
Location:112 → 286

FBA; F-box associated region