ba1l ba1 globin, like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ba1lprovided by ZNC
Official Full Name: ba1 globin, likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040901-4
See related: Ensembl:ENSDARG00000097238 AllianceGenome:ZFIN:ZDB-GENE-040901-4
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ba2; ba2l; hbba1.1; zgc:92900; si:dZ118J2.1; si:dz118j2.3; si:bY187G17.4
Summary: Predicted to enable heme binding activity and oxygen binding activity. Predicted to act upstream of or within oxygen transport. Predicted to be part of hemoglobin complex. Is expressed in blood. Human ortholog(s) of this gene implicated in sickle cell anemia. Orthologous to human HBE1 (hemoglobin subunit epsilon 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (55098457..55099272, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (54843855..54844670, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

hba1 (e-PCR)
- UniSTS:186966

U50380 (e-PCR)
- UniSTS:205677

fj04a05.x1 (e-PCR)
- UniSTS:198337

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables oxygen binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within oxygen transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of hemoglobin complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ba1 globin, like

Names: Beta-2-globin; Beta-A2-globin; HbB; Hemoglobin beta-2 chain; Hemoglobin subunit beta-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.