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FPV_gp5 large T antigen [ Finch polyomavirus ]

Gene ID: 5130561, updated on 18-Aug-2023

Summary

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Gene symbol
FPV_gp5
Gene description
large T antigen
Locus tag
FPV_gp5
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Finch polyomavirus (nat-host: Eurasian bullfinch (Pyrrhula pyrrhula griseiventris))
Lineage
Viruses; dsDNA viruses, no RNA stage; Polyomaviridae
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Genomic context

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Sequence:
NC_007923.1 (3236..5278, complement)

NC_007923.1Genomic Context describing neighboring genes Neighboring gene putative ORF-X Neighboring gene putative VP2 Neighboring gene putative VP3 Neighboring gene Major capsid protein VP1 Neighboring gene Small T antigen

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007923.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of two novel polyomaviruses of birds by using multiply primed rolling-circle amplification of their genomes. Johne R, et al. J Virol, 2006 Apr. PMID 16537620, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
large T antigen
YP_529834.1
  • large T antigen; binds to the viral origin of replication; regulates the transcription of early region mRNA; helicase activity facilitates movement of the virion DNA replication fork; the small T antigen shares a region in common with the large T antigen known as the J-domain; the J-domain is required for multiple processes including assembly, viral genomic DNA replication and transcription; The polyomaviruses are non-enveloped dsDNA viruses; the viral genome is organized into two divergent transcriptional units known as early and late regions; mRNAs from the early region encode the viral small and large t-antigens; the small T antigen and large T antigen are expressed upon entry into the host nucleus early in the viral lifecycle

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007923.1 Reference assembly

    Range
    3236..5278 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_529834.1 putative large T antigen [Finch polyomavirus]

    See identical proteins and their annotated locations for YP_529834.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I6RKC0, Q20HX6
    Conserved Domains (4) summary
    PHA02624
    Location:1 → 612
    PHA02624; large T antigen; Provisional
    pfam00226
    Location:9 → 53
    DnaJ; DnaJ domain
    pfam02217
    Location:120 → 214
    T_Ag_DNA_bind; Origin of replication binding protein
    pfam06431
    Location:244 → 591
    Polyoma_lg_T_C; Polyomavirus large T antigen C-terminus
Protein Accession Links
GenPept Link UniProtKB Link
ABB04274.1

Gene LinkOut

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Molecular Biology Databases
Research Materials