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CYRIB CYFIP related Rac1 interactor B [ Homo sapiens (human) ]

Gene ID: 51571, updated on 10-Dec-2024

Summary

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Official Symbol
CYRIBprovided by HGNC
Official Full Name
CYFIP related Rac1 interactor Bprovided by HGNC
Primary source
HGNC:HGNC:25216
See related
Ensembl:ENSG00000153310 MIM:617978; AllianceGenome:HGNC:25216
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
L1; CYRI; BM-009; CYRI-B; FAM49B
Summary
Enables small GTPase binding activity. Involved in several processes, including cellular response to molecule of bacterial origin; negative regulation of small GTPase mediated signal transduction; and regulation of organelle organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in bone marrow (RPKM 26.7), appendix (RPKM 26.4) and 24 other tissues See more
Orthologs
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Genomic context

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See CYRIB in Genome Data Viewer
Location:
8q24.21
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (129839593..130017129, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (130965555..131143607, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (130851839..131029375, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene CCDC26 long non-coding RNA Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:130526802-130527734 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:130527735-130528668 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19539 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27967 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27968 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27969 Neighboring gene microRNA 3686 Neighboring gene CRISPRi-validated CCDC26 and MYC e5 enhancer Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:130598970-130600169 Neighboring gene MPRA-validated peak7175 silencer Neighboring gene VISTA enhancer hs1709 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19540 Neighboring gene CRISPRi-validated CCDC26, MYC and PVT1 e6 enhancer Neighboring gene CRISPRi-validated CCDC26, MYC and PVT1 e7 enhancer Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:130719165-130720364 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:130722337-130723536 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:130725004-130725177 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27970 Neighboring gene mitochondrial translational release factor 1 like pseudogene 2 Neighboring gene gasdermin C Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:130844878-130845690 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:130845691-130846502 Neighboring gene uncharacterized LOC124900265 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:130881998-130882552 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:130882553-130883105 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27971 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:130899605-130900116 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:130899091-130899604 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27972 Neighboring gene MPRA-validated peak7177 silencer Neighboring gene ribosomal protein L15 pseudogene 12 Neighboring gene Sharpr-MPRA regulatory region 603 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19541 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27973 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:130957594-130958094 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:130971367-130971867 Neighboring gene MPRA-validated peak7178 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27974 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27975 Neighboring gene uncharacterized LOC124902025 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27976 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:131005193-131005693 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19542 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19543 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19544 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19545 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:131054337-131055152 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27979 Neighboring gene RNA, U7 small nuclear 181 pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr8:131067248-131067450 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:131081877-131082759 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27980 Neighboring gene microRNA 5194 Neighboring gene RNA, U6 small nuclear 1255, pseudogene Neighboring gene ASAP1 intronic transcript 2 Neighboring gene ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. A genome-wide genetic screen identifies CYRI-B as a negative regulator of CEACAM3-mediated phagocytosis. Kuiper JWP, et al. J Cell Sci, 2023 Jun 1. PMID 37264948
  2. Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation. Shang W, et al. Proc Natl Acad Sci U S A, 2018 Apr 24. PMID 29632189, Free PMC Article
  3. TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway. Zhang Y, et al. Int J Biol Sci, 2020. PMID 32071545, Free PMC Article
  4. Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1. Yelland T, et al. Structure, 2021 Mar 4. PMID 33217330, Free PMC Article
  5. GOLM1 and FAM49B: Potential Biomarkers in HNSCC Based on Bioinformatics and Immunohistochemical Analysis. Xi Y, et al. Int J Mol Sci, 2022 Dec 6. PMID 36499755, Free PMC Article

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake.
    Title: CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake.
  2. LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress.
    Title: LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress.
  3. A genome-wide genetic screen identifies CYRI-B as a negative regulator of CEACAM3-mediated phagocytosis.
    Title: A genome-wide genetic screen identifies CYRI-B as a negative regulator of CEACAM3-mediated phagocytosis.
  4. GOLM1 and FAM49B: Potential Biomarkers in HNSCC Based on Bioinformatics and Immunohistochemical Analysis.
    Title: GOLM1 and FAM49B: Potential Biomarkers in HNSCC Based on Bioinformatics and Immunohistochemical Analysis.
  5. Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1.
    Title: Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1.
  6. TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway.
    Title: TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway.
  7. CYFIP related Rac1 interactor B (CYRI) binds to the small GTPase RAC1 through a conserved domain present in CYFIP proteins. CYRI negatively regulates RAC1 signalling, thereby attenuating processes such as macropinocytosis, phagocytosis and cell migration. This enables CYRI to counteract Salmonella at various stages of infection. The bacterial effector SopE, a RAC1 activator, selectively targets CYRI following infection.
    Title: CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection.
  8. Low fam49B expression is associated with pancreatic ductal adenocarcinoma metastasis.
    Title: FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis.
  9. FAM49B inhibits T cell activation by repressing Rac activity and modulating cytoskeleton reorganization.
    Title: Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.
  10. Three proteins-matrix metalloproteinase-9, neutrophil elastase, and FAM49B-were significantly lower in abundance in samples from women with endometriosis.
    Title: Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals.
Submit: New GeneRIF Correction See all GeneRIFs (11)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association study identifies protein quantitative trait loci (pQTLs).
EBI GWAS Catalog
Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
EBI GWAS Catalog
Multiple loci are associated with white blood cell phenotypes.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • DKFZp686B04128

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables MHC class Ib protein binding, via antigen binding groove ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables small GTPase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to molecule of bacterial origin IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of small GTPase mediated signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of T cell activation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of T cell mediated cytotoxicity ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of memory T cell activation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of type II interferon production ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of chemotaxis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of mitochondrial fission IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cilium ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in extracellular exosome HDA PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in platelet alpha granule lumen TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
CYFIP-related Rac1 interactor B
Names
FAM49B/JPH1 fusion
MTSS1/FAM49B fusion
family with sequence similarity 49 member B
protein FAM49B

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256763.2 → NP_001243692.1  CYFIP-related Rac1 interactor B isoform 1

    See identical proteins and their annotated locations for NP_001243692.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variant 2 encode the same protein.
    Source sequence(s)
    AC022973, AK130372, BC003599, BX419336
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Related
    ENSP00000429499.1, ENST00000519540.5
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  2. NM_001330612.2 → NP_001317541.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AA975908, AC022973, CN362384, CX165551
    Consensus CDS
    CCDS83327.1
    UniProtKB/Swiss-Prot
    Q9NUQ9
    Related
    ENSP00000429978.1, ENST00000522250.5
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  3. NM_001353242.2 → NP_001340171.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an exon and includes three alternate exons in the 5' region, compared to variant 1.
    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Related
    ENSP00000384880.2, ENST00000401979.6
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  4. NM_001353243.2 → NP_001340172.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks two exons and includes three alternate exons in the 5' region, compared to variant 1.
    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Related
    ENSP00000429802.1, ENST00000523509.5
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  5. NM_001353244.2 → NP_001340173.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) includes two alternate internal exons, compared to variant 1.
    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Related
    ENSP00000428117.1, ENST00000522746.5
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  6. NM_001353245.1 → NP_001340174.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  7. NM_001353246.1 → NP_001340175.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  8. NM_001353247.1 → NP_001340176.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  9. NM_001353248.2 → NP_001340177.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  10. NM_001353249.1 → NP_001340178.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  11. NM_001353250.1 → NP_001340179.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Related
    ENSP00000429078.1, ENST00000519110.5
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  12. NM_001353251.1 → NP_001340180.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  13. NM_001353252.1 → NP_001340181.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  14. NM_001353253.1 → NP_001340182.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  15. NM_001353254.2 → NP_001340183.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  16. NM_001353255.1 → NP_001340184.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  17. NM_001353256.2 → NP_001340185.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  18. NM_001353257.2 → NP_001340186.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  19. NM_001353258.2 → NP_001340187.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Related
    ENSP00000511587.1, ENST00000694912.1
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  20. NM_001353259.2 → NP_001340188.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  21. NM_001353260.2 → NP_001340189.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Related
    ENSP00000430674.1, ENST00000517654.5
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  22. NM_001353261.2 → NP_001340190.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  23. NM_001353262.2 → NP_001340191.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  24. NM_001353263.2 → NP_001340192.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  25. NM_001353264.2 → NP_001340193.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  26. NM_001353265.2 → NP_001340194.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  27. NM_001353266.2 → NP_001340195.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  28. NM_001353267.2 → NP_001340196.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  29. NM_001353268.2 → NP_001340197.1  CYFIP-related Rac1 interactor B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  30. NM_001353269.1 → NP_001340198.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  31. NM_001353270.1 → NP_001340199.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  32. NM_001353271.1 → NP_001340200.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  33. NM_001353272.1 → NP_001340201.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  34. NM_001353273.1 → NP_001340202.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  35. NM_001353274.1 → NP_001340203.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  36. NM_001353275.1 → NP_001340204.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  37. NM_001353276.2 → NP_001340205.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  38. NM_001353277.1 → NP_001340206.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  39. NM_001353278.1 → NP_001340207.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  40. NM_001353279.1 → NP_001340208.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  41. NM_001353280.1 → NP_001340209.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  42. NM_001353281.1 → NP_001340210.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  43. NM_001353282.2 → NP_001340211.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  44. NM_001353283.2 → NP_001340212.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  45. NM_001353284.2 → NP_001340213.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  46. NM_001353285.2 → NP_001340214.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  47. NM_001353286.2 → NP_001340215.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  48. NM_001353287.2 → NP_001340216.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  49. NM_001353288.2 → NP_001340217.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  50. NM_001353289.2 → NP_001340218.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  51. NM_001353290.2 → NP_001340219.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  52. NM_001353291.2 → NP_001340220.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  53. NM_001353292.2 → NP_001340221.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  54. NM_001353293.2 → NP_001340222.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  55. NM_001353294.2 → NP_001340223.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  56. NM_001353295.2 → NP_001340224.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  57. NM_001353296.2 → NP_001340225.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  58. NM_001353297.2 → NP_001340226.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  59. NM_001353298.2 → NP_001340227.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  60. NM_001353299.2 → NP_001340228.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  61. NM_001353300.2 → NP_001340229.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  62. NM_001353301.2 → NP_001340230.1  CYFIP-related Rac1 interactor B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS83327.1
    Related
    ENSP00000430433.1, ENST00000522941.5
    Conserved Domains (1) summary
    pfam07159
    Location:1 → 174
    DUF1394; Protein of unknown function (DUF1394)

  63. NM_001353302.1 → NP_001340231.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Related
    ENSP00000515265.1, ENST00000703342.1
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  64. NM_001353303.1 → NP_001340232.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  65. NM_001353304.1 → NP_001340233.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  66. NM_001353305.1 → NP_001340234.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  67. NM_001353306.2 → NP_001340235.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  68. NM_001353307.2 → NP_001340236.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  69. NM_001353308.1 → NP_001340237.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  70. NM_001353309.1 → NP_001340238.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  71. NM_001353310.2 → NP_001340239.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  72. NM_001353311.2 → NP_001340240.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568, KF495742
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  73. NM_001353312.2 → NP_001340241.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  74. NM_001353313.2 → NP_001340242.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  75. NM_001353314.2 → NP_001340243.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  76. NM_001353315.2 → NP_001340244.1  CYFIP-related Rac1 interactor B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022973
    Consensus CDS
    CCDS94340.1
    UniProtKB/TrEMBL
    A0A8V8TMP7, Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  77. NM_001353316.2 → NP_001340245.1  CYFIP-related Rac1 interactor B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC022973, AC131568
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:17 → 312
    DUF1394; Protein of unknown function (DUF1394)

  78. NM_016623.5 → NP_057707.3  CYFIP-related Rac1 interactor B isoform 1

    See identical proteins and their annotated locations for NP_057707.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC022973, AK130372, BX419336
    Consensus CDS
    CCDS6361.1
    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Related
    ENSP00000429150.1, ENST00000519824.6
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    129839593..130017129 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047421855.1 → XP_047277811.1  CYFIP-related Rac1 interactor B isoform X2

    UniProtKB/TrEMBL
    Q68D08

  2. XM_011517121.4 → XP_011515423.2  CYFIP-related Rac1 interactor B isoform X1

  3. XM_047421856.1 → XP_047277812.1  CYFIP-related Rac1 interactor B isoform X3

    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08

  4. XM_024447180.2 → XP_024302948.1  CYFIP-related Rac1 interactor B isoform X3

    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
    Conserved Domains (1) summary
    pfam07159
    Location:18 → 320
    DUF1394; Protein of unknown function (DUF1394)

  5. XM_047421859.1 → XP_047277815.1  CYFIP-related Rac1 interactor B isoform X3

    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08

  6. XM_047421857.1 → XP_047277813.1  CYFIP-related Rac1 interactor B isoform X3

    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    130965555..131143607 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054360636.1 → XP_054216611.1  CYFIP-related Rac1 interactor B isoform X2

    UniProtKB/TrEMBL
    Q68D08

  2. XM_054360635.1 → XP_054216610.1  CYFIP-related Rac1 interactor B isoform X1

  3. XM_054360638.1 → XP_054216613.1  CYFIP-related Rac1 interactor B isoform X3

    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08

  4. XM_054360637.1 → XP_054216612.1  CYFIP-related Rac1 interactor B isoform X3

    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08

  5. XM_054360640.1 → XP_054216615.1  CYFIP-related Rac1 interactor B isoform X3

    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08

  6. XM_054360639.1 → XP_054216614.1  CYFIP-related Rac1 interactor B isoform X3

    UniProtKB/Swiss-Prot
    Q96AZ5, Q9NUQ9, Q9NW21, Q9NZE7
    UniProtKB/TrEMBL
    Q68D08
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9NUQ9.1 GenPept UniProtKB/Swiss-Prot:Q9NUQ9

Gene LinkOut

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